Hip geometry and femoral neck fractures: A meta-analysis.

Hip geometry and femoral neck fractures: A meta-analysis.
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DOI:
10.1016/j.jot.2017.12.002
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发表时间:
2018-04
影响因子:
6.6
通讯作者:
Azharuddin A
Azharuddin A
中科院分区:
医学2区
文献类型:
--
作者:
Fajar JK;Taufan T;Syarif M;Azharuddin A

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几项研究报告了髋关节几何结构预测股骨颈骨折。然而,他们表现出不一致。确定髋关节几何形状与股骨颈骨折之间的关系。检索了PubMed和Embase数据库(截至2017年5月25日)中的已发表文献,以寻找合格的出版物。提取了与(1)第一作者姓名;(2)发表年份;(3)来源国;(4)病例和对照样本量以及(5)病例和对照的平均值和标准差相关的信息。使用随机或固定效应模型评估髋关节几何形状与股骨颈骨折之间相关性的合并比值比(OR)和95%置信区间(95% CI)。采用2.0版综合荟萃分析软件对数据进行分析。本研究共纳入11项研究。我们的研究结果表明,增加髋轴长度,(OR 95% CI = 1.53 [1.06-2.21],p = 0.025),股骨颈角(OR 95% CI = 1.47 [1.01-2.15],p = 0.044)和颈宽(OR 95% CI = 2.68 [1.84-3.91],p < 0.001)与股骨颈骨折风险相关,而股骨颈轴长与股骨颈骨折的危险性无相关性。有强有力的证据表明,髋轴长度、股骨颈角度和股骨颈宽度的增加是股骨颈骨折的危险因素。这篇文章的翻译潜力:确定与股骨颈骨折高度相关的髋关节轴长、股骨颈角和股骨颈宽度,可以让临床医生更准确地预测哪些人将来可能发生股骨颈骨折。
Several studies have reported hip geometry to predict the femoral neck fractures. However, they showed inconsistency. To determine the association between hip geometry and femoral neck fractures. Published literature from PubMed and Embase databases (until May 25th, 2017) was searched for eligible publications. The information related to (1) name of first author; (2) year of publication; (3) country of origin; (4) sample size of cases and controls and (5) mean and standard deviation of cases and controls were extracted. The pooled odds ratios (ORs) and 95% confidence intervals (95% CIs) for the association between hip geometry and femoral neck fractures were assessed using random or fixed effect model. A Comprehensive Meta-analysis software, version 2.0, was used to analyse the data. A total of 11 studies were included in this study. Our results showed that increase in hip axis length (OR 95% CI = 1.53 [1.06–2.21], p = 0.025), femoral neck angle (OR 95% CI = 1.47 [1.01–2.15], p = 0.044) and neck width (OR 95% CI = 2.68 [1.84–3.91], p < 0.001) was associated with the risk of femoral neck fractures, whereas we could not find the correlation between femoral neck axis length and the risk of femoral neck fractures. There is strong evidence that elevated hip axis length, femoral neck angle and neck width are the risk factor for femoral neck fractures. The Translational Potential of this Article: Determining the hip axis length, femoral neck angle and neck width that are most highly associated with femoral neck fracture may allow clinicians to more accurately predict which individuals are likely to experience femoral neck fractures in the future.
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