Intima-media thickness remodelling in hypertensive subjects with long-term well-controlled blood pressure levels
Intima-media thickness remodelling in hypertensive subjects with long-term well-controlled blood pressure levels
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DOI：
10.1080/08037051.2016.1184964
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发表时间：
2017-02-01
期刊：
影响因子：
1.8
通讯作者：
Pauletto, Paolo
中科院分区：
文献类型：
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作者：
Puato, Massimo;Boschetti, Giovanni;Pauletto, Paolo
本研究的目的是在长期随访中评估血压控制良好的年轻高血压患者的颈动脉重构。我们对20例I级高血压患者（HT）进行了双侧颈动脉各段（普通、球状、内）的平均颈动脉内膜-中膜厚度（mean-IMT）和最大IMT （M-MAX）的b超评估。我们将他们的超声测量结果与5年和10年前的记录进行了比较。第一个5年随访是观察性的，在第二个5年随访中，开始改变生活方式和/或药物治疗，以获得良好控制的血压水平。在超声检查时测量办公室血压，并在随访期间每6个月测量一次。研究时的血压水平为：10年144/91mmHg， 5年143/90mmHg和129 +/- 79mmHg。在第一个5年的观察随访中，平均imt和M-MAX分别增加了0.116和0.165mm, p
Aim of this study was to evaluate in a long follow-up the carotid artery remodelling in a cohort of young hypertensive subjects having good blood pressure (BP) control. We studied 20 grade I hypertensives (HT) by assessing the B-mode ultrasound of mean carotid intima-media thickness (mean-IMT) and maximum IMT (M-MAX) in each carotid artery segment (common, bulb, internal), bilaterally. We compared their ultrasound measurements with those recorded 5 and 10 years earlier. While the first 5-year follow-up was observational, in the second 5-year follow-up, lifestyle modifications and/or pharmacological therapy were started to obtain well-controlled BP levels. Office BP was measured at the time of the ultrasound studies and every 6 months during the follow-up. BP levels were: 10 years 144/91mmHg, 5 years 143/90mmHg and 129 +/- 79mmHg at the time of the study. In the first 5-year observational follow-up, both mean-IMT and M-MAX increased ( 0.116 and 0.165mm, respectively, p