A three-step method for modular lymphadenectomy in gastric cancer surgery: The ability to retrieve sufficient lymph nodes and improve survival

A three-step method for modular lymphadenectomy in gastric cancer surgery: The ability to retrieve sufficient lymph nodes and improve survival
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胃癌手术中模块化淋巴结切除术的三步法:能够检索足够的淋巴结并提高生存率

DOI:
10.1016/j.amjsurg.2017.01.042
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发表时间:
2018-01-01
影响因子:
3
通讯作者:
Liu, Yingbin
Liu, Yingbin
中科院分区:
医学3区
文献类型:
--
作者:
Li, Maolan;Wang, Xu-an;Liu, Yingbin

文献摘要

被引文献

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背景资料:系统性淋巴结清扫术是胃癌根治性切除术的重要组成部分。在这里,我们探讨了三步法的模块化淋巴结清扫术(TSMML)的结果,并确定其安全性和有效性,与传统的淋巴结清扫术(CML)方法:从2008年至2011年,270例胃癌患者分为2个亚组:TSMML组和CML组。与CML组相比,TSMML组患者的中位回收淋巴结数(rLN)显著较高,中位转移淋巴结比率(MLR)较低,且上级5年无复发生存率(RFS)较高。此外,使用TSMML程序是RFS的独立保护因素。结论:TSMML手术操作简单、安全、有效。(c)2017爱思唯尔公司All rights reserved.
Background: Systematic lymphadenectomy for the resection of sufficient lymph nodes is the most important part of curative resection in gastric cancer surgery. Here, we explore the outcomes of the three-step method for modular lymphadenectomy (TSMML) and determine its safety and efficacy, compared with the conventional method for lymphadenectomy (CML).Methods: From 2008 to 2011, 270 patients with gastric cancer were divided into 2 subgroups: the TSMML group and the CML group.Results: Patients in the TSMML group had a significantly higher median number of retrieved lymph nodes (rLNs), lower median metastatic lymph node ratios (MLRs), and superior 5-year relapse-free survival (RFS) than the CML group. Moreover, the use of the TSMML procedure was an independent protective factor for RFS. No significant intergroup differences were found in morbidity or mortality in these two groups.Conclusion: The TSMML procedure is safe and effective and is easy to learn. (c) 2017 Elsevier Inc. All rights reserved.