BIOCHEMICAL MATURATION OF HUMAN CENTRAL NERVOUS SYSTEM MYELIN 1
BIOCHEMICAL MATURATION OF HUMAN CENTRAL NERVOUS SYSTEM MYELIN 1
复制标题
人类中枢神经系统髓磷脂 1 的生化成熟
DOI：
10.1111/j.1471-4159.1975.tb03849.x
复制
发表时间：
1975
影响因子：
4.7
通讯作者：
R. F. Mitchell
中科院分区：
文献类型：
--
作者：
M. Fishman;H. Agrawal;A. Alexander;J. Golterman;R. Martenson;R. F. Mitchell
- 对人类中枢神经系统髓鞘的脂质和蛋白质组成进行了发育研究。主要脂质类（胆固醇、糖脂和磷脂）的相对浓度几乎没有变化，但磷脂浓度略有下降。与总磷脂相比，发现单个磷脂的相对浓度有显著变化，鞘磷脂增加了两倍多，磷脂酰胆碱几乎减少到原来浓度的一半。
—A developmental study of the lipid and protein composition of human CNS myelin was undertaken. The relative concentrations of the major lipid classes, cholesterol, glycolipids and phospholipids exhibited little change except for a modest decrease in the concentration of the phospholipids. In contrast to the total phospholipids, marked variations in the relative concentrations of individual phospholipids were found. Sphingomyelin increased over two‐fold, and phosphatidyl choline decreased to almost half its original concentration.