The effects of essential oils and aqueous tea infusions of oregano (Origanum vulgare L. spp. hirtum), thyme (Thymus vulgaris L.) and wild thyme (Thymus serpyllum L.) on the copper-induced oxidation of human low-density lipoproteins
The effects of essential oils and aqueous tea infusions of oregano (Origanum vulgare L. spp. hirtum), thyme (Thymus vulgaris L.) and wild thyme (Thymus serpyllum L.) on the copper-induced oxidation of human low-density lipoproteins
复制标题
DOI：
10.1080/09637480601108307
复制
发表时间：
2007-03-01
影响因子：
3.9
通讯作者：
Pifat, Greta
中科院分区：
文献类型：
--
作者：
Kulisic, Tea;Krisko, Anita;Pifat, Greta
在这项研究中，从牛至，百里香和野生百里香的氧化敏感性的低密度脂蛋白（LDL）的精油和水茶输液的抗氧化能力的影响进行了研究。结果表明，测试的精油和含水茶输液对铜诱导的LDL氧化的剂量依赖性保护作用。精油的保护作用归因于酚类单萜、百里酚和香芹酚的存在，它们被鉴定为这些精油中的主要化合物。水性茶浸液的强保护作用被认为是大量多酚的结果，即迷迭香酸和类黄酮（槲皮素、圣草苷、木犀草素-7-0-葡萄糖苷、芹菜素-7-0-葡萄糖苷、木犀草素、芹菜素），在牛至的情况下效果最显著。这些发现可能对这些化合物在体内对LDL的作用有影响。
In this study, the antioxidative capacity effect of essential oils and aqueous tea infusions obtained from oregano, thyme and wild thyme on the oxidation susceptibility of low-density lipoproteins (LDL) has been studied. The results indicate a dose-dependent protective effect of the tested essential oils and aqueous tea infusions on the copper-induced LDL oxidation. The protective effect of essential oils is assigned to the presence of phenolic monoterpenes, thymol and carvacrol, which are identified as the dominant compounds in these essential oils. The strong protective effect of aqueous tea infusions is proposed to be the consequence of large amounts of polyphenols, namely rosmarinic acid and flavonoids (quercetin, eriocitrin, luteolin-7-O-glucoside, apigenin-7-O-glucoside, luteolin, apigenin), with the most pronounced effect in the case of oregano. These findings may have implications for the effect of these compounds on LDL in vivo.