A reassessment of trends in the medical use and abuse of opioid analgesics and implications for diversion control: 1997-2002
A reassessment of trends in the medical use and abuse of opioid analgesics and implications for diversion control: 1997-2002
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DOI：
10.1016/j.jpainsymman.2004.01.003
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发表时间：
2004-08-01
影响因子：
4.7
通讯作者：
Dahl, JL
中科院分区：
文献类型：
--
作者：
Gilson, AM;Ryan, KM;Dahl, JL
这项研究更新了先前对阿片类镇痛药的医疗使用和滥用趋势的分析，并提供了1997年至2002年的数据。我们评估了两个研究问题：1)用于治疗严重疼痛的常用阿片类镇痛药（包括芬太尼、氢吗啡酮、哌替啶、吗啡和羟考酮）的医疗使用和滥用趋势如何？2)与其他药物类别的滥用趋势相比，阿片类镇痛药的滥用趋势是什么？结果表明，在研究的五种阿片类镇痛药中，有四种的医疗使用和滥用情况明显增加。2002年，阿片类镇痛药占所有药物滥用的9.85%，高于1997年的5.75%。类阿片医疗使用的增加是缓解疼痛取得进展的一般指标。类阿片滥用的增加是一个日益严重的公共卫生问题，应在不干扰合法医疗实践和病人护理的情况下，通过查明转移用途的原因和来源来加以解决。(C) 2004美国癌症疼痛缓解委员会。Elsevier Inc.出版。版权所有。
This study updates a previous analysis of trends in medical use and abuse of opioid analgesics, and provides data from 1997 through 2002. Two research questions wee evaluated: 1) Mat are the trends in the medical use and abuse of frequently prescribed opioid analgesics used to treat severe, pain, including,fentanyl, hydromorphone, meperidine, morphine, and oxycodone? 2) What is the abuse trend for opioid analgesics as a class compared to trends in the abuse of other drug classes? Results demonstrated marked increases in medical use and abuse of four of the five studied opioid analgesics. In 20022, opioid analgesics accounted for 9.85% of all drug abuse, up from 5.75% in 1997. Increase in medical use of opioids is a general indicator of progress in providing pain relief. Increases in abuse of opioids is a growing public health problem and should be addressed by identifying the causes and sources of diversion, without interfering with legitimate medical practice and patient care. (C) 2004 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.