Planar radionuclide angiography with a dedicated cardiac SPECT camera
Planar radionuclide angiography with a dedicated cardiac SPECT camera
复制标题
使用专用心脏 SPECT 相机进行平面放射性核素血管造影
DOI：
10.1007/s12350-013-9674-6
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发表时间：
2011
影响因子：
2.4
通讯作者：
T. Ruddy
中科院分区：
文献类型：
--
作者：
R. Wells;Brian Marvin;Gil Kovalski;T. Ruddy
背景我们比较了一种专用的心脏照相机和一种传统的使用门控血池成像测量左心室（LV）功能的系统。方法在标准伽马照相机上，从LAO方向获得48例患者的24帧门控平面图像，6 M计数/视图。此后立即在专用心脏SPECT相机上获得8分钟的24帧ECG门控数据。迭代重建门控SPECT图像体积，然后离线传输。使用内部软件将图像重新投影为24帧门控平面格式。使用半自动软件分析原始和重新投影的门控平面数据集，以确定射血分数（EF），心室容积（舒张末期容积，EDV），峰值射血率（PER）和峰值充盈率（PFR）。EF的相关性r ≥ 0.94（P<0.01），线性回归斜率为0.98。EDV的相关性r ≥ 0.86（P<0.01），但专用心脏摄像机的体积较小（线性回归斜率为0.6）。PFR和PER的相关性分别为r = 0.91和r ≥ 0.83（两者均P<0.01）。结论24帧门控血池SPECT图像的再投影是使用标准2D平面分析工具的专用心脏SPECT相机获得LV功能测量的有效手段。
BackgroundWe compared a dedicated cardiac camera with a traditional system for left ventricular (LV) functional measurements using gated blood-pool imaging.Methods24-frame gated planar images were obtained from 48 patients in an LAO orientation for 6M counts/view on a standard gamma camera. Immediately thereafter, 24-frame ECG-gated data were obtained for 8 minutes on a dedicated cardiac SPECT camera. The gated SPECT image volumes were iteratively reconstructed and then transferred offline. In-house software was used to reproject the images into a 24-frame gated planar format. Both the original and the reprojected gated planar datasets were analyzed using semiautomated software to determine ejection fraction (EF), ventricular volume (end diastolic volume, EDV), peak ejection rate (PER), and peak filling rate (PFR).ResultsThe difference in EF values averaged 0.4% ± 4.4%. The correlation in EF wasr≥ 0.94 (P< .01) with a linear regression slope of 0.98. Correlation of the EDV wasr≥ 0.86 (P< .01), but the volumes from the dedicated cardiac camera were smaller (linear regression slope was 0.6). Correlation of PFR and PER werer= 0.91 andr≥ 0.83, respectively (P< .01 for both).ConclusionsReprojection of 24-frame gated blood-pool SPECT images is an effective means of obtaining LV functional measurements with a dedicated cardiac SPECT camera using standard 2D-planar analysis tools.