Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trial.
Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trial.
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DOI：
10.1016/s0140-6736(11)60701-0
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发表时间：
2011-07-02
期刊：
影响因子：
168.9
通讯作者：
Roberts, Ian
中科院分区：
文献类型：
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作者：
Free, Caroline;Knight, Rosemary;Robertson, Steven;Whittaker, Robyn;Edwards, Phil;Zhou, Weiwei;Rodgers, Anthony;Cairns, John;Kenward, Michael G.;Roberts, Ian
通过手机短信发送的戒烟计划显示，在短期内，自我报告戒烟的人数会增加。我们评估了通过手机短信发送的自动戒烟程序对持续戒烟的影响，并在6个月时进行了生化验证。在英国进行的这项单盲随机试验中，愿意尝试戒烟的吸烟者使用独立的电话随机系统被随机分配到手机短信戒烟计划(Txt2top)中，该计划包括激励信息和行为改变支持，或者被分配到接收与戒烟无关的短信的对照组。系统根据分配情况自动生成干预组或控制组文本。结果评估员被蒙面进行治疗分配。主要结果是自我报告的持续戒烟，在6个月时进行生化验证。所有分析均为意向治疗。这项研究已注册，编号为ISRCTN 80978588。我们评估了11名 914参与者的资格。5800名参与者被随机分配，其中2915名吸烟者被分配到txt2top干预组，2885名被分配给对照组；8名被排除在外，因为他们被随机分配了不止一次。5524名(95%)参与者获得了主要结果数据。经生化证实的持续戒断6个月，TXT2组显著高于对照组(10.7%TXT2与4.9%对照组，相对危险度[RR]2·20，95%CI 1·80-2·68；p<；0·0001)。当失去随访的参与者被视为吸烟者时(2911名txt2top中的268名[9%]对2881名对照组的124名[4%][RR 2·14，95%CI 1·74-2·63；p<；0·0001])，以及当他们被排除在外时(2735名txt2top中的268名[10%]对2789名对照组的124[4%][2.20，1·79-2·71；p<；0·0001])。在任何预先指定的亚组中都没有表现出显著的异质性。Txt2戒烟方案在6个月后显著提高了戒烟率，应考虑纳入戒烟服务。英国医学研究委员会，初级保健研究网络。
Smoking cessation programmes delivered via mobile phone text messaging show increases in self-reported quitting in the short term. We assessed the effect of an automated smoking cessation programme delivered via mobile phone text messaging on continuous abstinence, which was biochemically verified at 6 months. In this single-blind, randomised trial, undertaken in the UK, smokers willing to make a quit attempt were randomly allocated, using an independent telephone randomisation system, to a mobile phone text messaging smoking cessation programme (txt2stop), comprising motivational messages and behavioural-change support, or to a control group that received text messages unrelated to quitting. The system automatically generated intervention or control group texts according to the allocation. Outcome assessors were masked to treatment allocation. The primary outcome was self-reported continuous smoking abstinence, biochemically verified at 6 months. All analyses were by intention to treat. This study is registered, number ISRCTN 80978588. We assessed 11 914 participants for eligibility. 5800 participants were randomised, of whom 2915 smokers were allocated to the txt2stop intervention and 2885 were allocated to the control group; eight were excluded because they were randomised more than once. Primary outcome data were available for 5524 (95%) participants. Biochemically verified continuous abstinence at 6 months was significantly increased in the txt2stop group (10·7% txt2stop vs 4·9% control, relative risk [RR] 2·20, 95% CI 1·80–2·68; p<0·0001). Similar results were obtained when participants that were lost to follow-up were treated as smokers (268 [9%] of 2911 txt2stop vs 124 [4%] of 2881 control [RR 2·14, 95% CI 1·74–2·63; p<0·0001]), and when they were excluded (268 [10%] of 2735 txt2stop vs 124 [4%] of 2789 control [2·20, 1·79–2·71; p<0·0001]). No significant heterogeneity was shown in any of the prespecified subgroups. The txt2stop smoking cessation programme significantly improved smoking cessation rates at 6 months and should be considered for inclusion in smoking cessation services. UK Medical Research Council, Primary Care Research Networks.