Cerebral oxygenation and hemodynamic changes during infant cardiac surgery: measurements by near infrared spectroscopy.
Cerebral oxygenation and hemodynamic changes during infant cardiac surgery: measurements by near infrared spectroscopy.
复制标题
婴儿心脏手术期间的脑氧合和血流动力学变化：近红外光谱测量。
DOI：
10.1117/12.251467
复制
发表时间：
1996
影响因子：
3.5
通讯作者：
J. Volpe
中科院分区：
文献类型：
--
作者：
A. du Plessis;J. Volpe
尽管接受先天性心脏病心脏手术的婴儿的存活率有了显著提高，但幸存者脑损伤的发生率仍然高得令人无法接受。这在很大程度上是由于我们对术中由于低温、神经活性药物和深刻的循环变化而发生的脑氧利用和供应的复杂变化的理解有限。脑氧供应和利用充足性监测技术的现状
低温心脏手术不足以解决这一复杂问题，
婴儿有这种脑损伤的风险。此外，这种无法检测即将发生的缺氧缺血性脑损伤可能会变得更加明显，因为新的神经保护策略，能够挽救“受损”的神经组织免于细胞死亡，进入临床竞技场。近红外光谱是一种相对
新的，非侵入性的，便携式的技术，能够询问氧合和血流动力学，
体内组织。该技术的这些特征在临床医生中产生了巨大的兴趣，近红外光谱能够阐明术中脑损伤的机制，并最终识别有这种损伤风险的婴儿。本文回顾了迄今为止在婴儿心脏手术中使用该技术的经验。
Despite dramatic advances in the survival rate amongst infants undergoing cardiac surgery for congenital heart disease, the incidence of brain injury suffered by survivors remains unacceptably high. This is largely due to our limited understanding of the complex changes in cerebral oxygen utilization and supply occurring during the intraoperative period as a result of hypothermia, neuroactive drugs, and profound circulatory changes. Current techniques for monitoring the adequacy of cerebral oxygen supply and utilization during
hypothermic cardiac surgery are inadequate to address this complex problem and consequently to identify
the infant at risk for such brain injury. Furthermore, this inability to detect imminent hypoxic-ischemic brain injury is likely to become all the more conspicuous as new neuroprotective strategies, capable of salvaging ‘‘insulted’’ neuronal tissue from cell death, enter the clinical arena. Near infrared spectroscopy is a relatively
new, noninvasive, and portable technique capable of interrogating the oxygenation and hemodynamics of
tissue in vivo. These characteristics of the technique have generated enormous interest amongst clinicians in the ability of near infrared spectroscopy to elucidate the mechanisms of intraoperative brain injury and ultimately to identify infants at risk for such injury. This paper reviews the experience with this technique to date during infant cardiac surgery.
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影响因子：
8
作者：
Altman,DI;Perlman,JM;Volpe,JJ;Powers,WJ
通讯作者：
Powers,WJ
根据速度测量计算脑动脉血流量的有效性。
影响因子：
8.3
作者：
Kontos,HA
通讯作者：
Kontos,HA
通过近红外光谱测量仔猪体外循环和深低温停循环期间的脑氧合。
DOI：
10.1203/00006450-199612000-00003
发表时间：
1996
期刊：
Pediatric research.
影响因子：
--
作者：
Nomura,F;Naruse,H;duPlessis,A;Hiramatsu,T;Forbess,J;Holtzman,D;Volpe,JJ;Jonas,R;Tsuji,M
通讯作者：
Tsuji,M
停循环前后的 pH 策略和脑能量学。
DOI：
10.1016/s0022-5223(95)70321-7
发表时间：
1995
期刊：
The Journal of thoracic and cardiovascular surgery.
影响因子：
--
作者：
Hiramatsu,T;Miura,T;Forbess,JM;DuPlessis,A;Aoki,M;Nomura,F;Holtzman,D;Jonas,RA
通讯作者：
Jonas,RA
低体温循环停止或低流量心肺旁路心脏手术后儿童的发育和神经状况
影响因子：
158.5
作者：
BELLINGER, DC;JONAS, RA;NEWBURGER, JW
通讯作者：
NEWBURGER, JW