POLYPOIDAL CHOROIDAL VASCULOPATHY Simultaneous Indocyanine Green Angiography and Eye-Tracked Spectral Domain Optical Coherence Tomography Findings
POLYPOIDAL CHOROIDAL VASCULOPATHY Simultaneous Indocyanine Green Angiography and Eye-Tracked Spectral Domain Optical Coherence Tomography Findings
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DOI：
10.1097/iae.0b013e31823beb14
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发表时间：
2012-06-01
影响因子：
3.3
通讯作者：
Freund, K. Bailey
中科院分区：
文献类型：
--
作者：
Khan, Samira;Engelbert, Michael;Freund, K. Bailey
目的：描述息肉状脉络膜血管病变（PCV）患者同时扫描激光检眼镜吲哚菁绿色血管造影和眼跟踪光谱域光学相干断层扫描的结果。对18例不同诊断的PCV患者的18只眼进行了同步扫描激光检眼镜、吲哚菁绿色血管造影和眼跟踪光谱成像。区域光学相干断层扫描定位息肉及其相关血管结构相对于视网膜层。结果：不管潜在的诊断，同步扫描激光检眼镜吲哚菁绿色血管造影和眼跟踪光谱-域光学相干断层扫描成像将PCV的息肉状结构定位于发生在布鲁赫膜内或上方的较大的1型新生血管复合体内。在8只眼睛中，PCV似乎粘附于升高的视网膜色素上皮脱离的下表面。在1只眼睛，PCV病变内检测到的神经感觉性视网膜已明显侵蚀通过覆盖的视网膜色素epitheliates.Conclusion：同时扫描激光检眼镜吲哚菁绿色血管造影和眼跟踪光谱域光学相干断层扫描表明，大多数PCV代表的1型新生血管生长模式的变体，它可以发生在各种不同的新生血管化黄斑病变。息肉状脉络膜血管病变似乎起源于长期存在的脉络膜新生血管，而不是脉络膜血管本身。鉴于这些观察结果，PCV更准确地描述为新血管病变，而不是脉络膜血管病变。视网膜32：1057-1068，2012
Purpose: To describe simultaneous scanning laser ophthalmoscope indocyanine green angiographic and eye-tracked spectral-domain optical coherence tomography findings in eyes with polypoidal choroidal vasculopathy (PCV).Methods: Eighteen eyes of 18 patients with PCV because of a variety of different diagnoses were imaged with simultaneous scanning laser ophthalmoscope indocyanine green angiography and eye-tracked spectral-domain optical coherence tomography to localize the polyps and their associated vascular structures with respect to the retinal layers.Results: Regardless of the underlying diagnosis, simultaneous scanning laser ophthalmoscope indocyanine green angiography and eye-tracked spectral-domain optical coherence tomography imaging localized the polypoidal structures of PCV to within larger Type 1 neovascular complexes occurring within or above Bruch membrane. In 8 eyes, PCV appeared to adhere to the undersurface of an elevated retinal pigment epithelial detachment. In 1 eye, a PCV lesion was detected within the neurosensory retina having apparently eroded through the overlying retinal pigment epithelium.Conclusion: Simultaneous scanning laser ophthalmoscope indocyanine green angiography and eye-tracked spectral-domain optical coherence tomography demonstrate that a majority of PCV represents a variant of the Type 1 neovascular growth pattern, which can occur in a variety of different neovascularized maculopathies. Polypoidal choroidal vasculopathy lesions appear to originate from long-standing choroidal neovascularization, rather than from the choroidal vasculature itself. Given these observations, PCV would be more accurately described as a neovasculopathy rather than as a choroidal vasculopathy. RETINA 32: 1057-1068, 2012