Reference Values for Central Airway Dimensions on CT Images of Children and Adolescents
Reference Values for Central Airway Dimensions on CT Images of Children and Adolescents
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DOI：
10.2214/ajr.17.18597
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发表时间：
2018-02-01
影响因子：
5
通讯作者：
Tiddens, Harm A. W. M.
中科院分区：
文献类型：
--
作者：
Kuo, Wieying;Ciet, Pierluigi;Tiddens, Harm A. W. M.
OBJECTIVE.本研究的目的是在儿科人群中获得胸部CT扫描中心气道尺寸的标准数据。在10个国际中心回顾性收集了放射科医生报告为正常的胸部CT结果。由一名经验丰富的独立胸部放射科医生重新评价所有CT扫描的图像质量和正常结果。进行半自动图像分析以测量吸气时气管和左右主支气管的尺寸。测量从隆突到胸廓入口的胸内气管长度。从隆突开始，垂直于纵向气道轴测量横截面积和短轴和长轴，对于气管向上每厘米，对于主支气管向下每0.5 cm。使用混合效应模型分析，研究年龄、性别、胸内气管长度和距隆突的距离对气道直径的影响。在收集的1160个CT扫描中，388个被独立放射科医师评价为正常，具有足够的图像质量和足够的吸气量水平。在388项CT研究中，有294项成功地半自动分析了中央气道。年龄、性别、胸内气管长度和距隆突的距离都是模型中气管和左右主支气管直径的显著预测因素（p < 0.001）。20岁以下患者中心气道直径随年龄增长而增大，男性大于女性。确定儿童和青少年中央气道的规范性数据。中心气道的大小取决于距隆突的距离和胸内气管的长度。
OBJECTIVE. The purpose of this study was to acquire normative data on central airway dimensions on chest CT scans in the pediatric population.MATERIALS AND METHODS. Chest CT findings reported as normal by a radiologist were collected retrospectively at 10 international centers. An experienced and independent thoracic radiologist reevaluated all CT scans for image quality and for normal findings. Semiautomated image analysis was performed to measure dimensions of the trachea and right and left main bronchi at inspiration. Intrathoracic tracheal length was measured from carina to thorax inlet. Cross-sectional area and short and long axes were measured perpendicular to the longitudinal airway axis starting from the carina every centimeter upward for the trachea and every 0.5 cm downward for the main bronchi. The effects on airway diameters of age, sex, intrathoracic tracheal length, and distance from the carina were investigated by use of mixed-effects models analysis.RESULTS. Among 1160 CT scans collected, 388 were evaluated as normal by the independent radiologist with sufficient image quality and adequate inspiratory volume level. Central airways were successfully semiautomatically analyzed in 294 of 388 CT studies. Age, sex, intrathoracic tracheal length, and distance from carina were all significant predictors in the models for tracheal and right and left main bronchial diameters (p < 0.001). The central airway dimensions increased with age up to 20 years, and dimensions were larger in male than in female adolescents.CONCLUSION. Normative data were determined for the central airways of children and adolescents. Central airway dimensions depended on distance from the carina and on intrathoracic tracheal length.