New frontiers in metabolomics: from measurement to insight.
New frontiers in metabolomics: from measurement to insight.
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DOI：
10.12688/f1000research.11495.1
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Powers R
中科院分区：
文献类型：
--
作者：
Riekeberg E;Powers R
代谢组学是“组学”学科的最新成员，由于测量和分析技术的基本进步，它在人类健康研究中的应用显示出快速增长。代谢组学在系统生物学和生物标志物发现方面具有独特的优势。下一代分析技术承诺更丰富、更完整的分析能力，将使早期临床诊断、药物改进和个性化医疗成为可能。综述了目前在方法和统计分析方面的进展，这些进展正在增强和改善代谢组学的性能，并介绍了一些最近成功的应用。
Metabolomics is the newest addition to the “omics” disciplines and has shown rapid growth in its application to human health research because of fundamental advancements in measurement and analysis techniques. Metabolomics has unique and proven advantages in systems biology and biomarker discovery. The next generation of analysis techniques promises even richer and more complete analysis capabilities that will enable earlier clinical diagnosis, drug refinement, and personalized medicine. A review of current advancements in methodologies and statistical analysis that are enhancing and improving the performance of metabolomics is presented along with highlights of some recent successful applications.