CONCENTRATION OF SALIVARY IODIDE - A COMPARATIVE STUDY
CONCENTRATION OF SALIVARY IODIDE - A COMPARATIVE STUDY
复制标题
DOI：
10.1113/jphysiol.1959.sp006165
复制
发表时间：
1959-01-01
影响因子：
5.5
通讯作者：
MYANT, NB
中科院分区：
文献类型：
--
作者：
COHEN, B;MYANT, NB
在人、犬、小鼠、仓鼠、豚鼠和棉鼠中，唾液腺对I131的浓缩能力较高;在乳鼠属和猫中为中度;在兔中较弱，在大鼠中可忽略不计。在人类中，碘化物的浓度由腮腺和下颌下腺产生;在犬中由腮腺产生;在小鼠、仓鼠和乳鼠中由下颌下腺产生;在豚鼠和棉鼠中由腮腺产生，也可能由下颌下腺和舌下产生。在猫和兔子中，浓度是由于软腭和脸颊相邻部分的腺体分泌物引起的。唾液腺的组织学检查没有发现含有碘化物浓缩机制的腺体所特有的特殊类型的细胞。在一名服用I131后死亡的人中，腮腺和颌下腺含有超过95%的被鉴定为碘化物的I131。
I131 concentrating power by salivary glands was high in humans, dogs, mice, hamsters, guinea pigs and cotton-rats; moderate in Mastomys and cats; weak in rabbits, and negligible in rats. In humans, concentration of iodide was produced by the parotid and submandibular glands; in dogs by the parotid; in mice, hamsters, and Mastomys by the submandibular; in guinea pigs and cotton-rats by the parotid and possible also by the submandibular and sublingual. In cats and rabbits, concentration was due to secretion by the glands of the soft palate and the adjacent part of the cheek. Histological examination of the salivary glands revealed no special type of cell peculiar to the glands containing the iodide-concentrating mechanism. In a human who had died after a dose of I131, the parotid and submandibular glands contained more than 95% of the I131 identified as iodide.