ULTRASTRUCTURAL ORGANIZATION OF RAT EXOCRINE PANCREAS .2. CENTROACINAR CELLS, INTERCALARY AND INTRALOBULAR DUCTS
ULTRASTRUCTURAL ORGANIZATION OF RAT EXOCRINE PANCREAS .2. CENTROACINAR CELLS, INTERCALARY AND INTRALOBULAR DUCTS
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DOI：
10.1016/s0022-5320(62)80028-8
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发表时间：
1962-01-01
期刊：
影响因子：
--
通讯作者：
ZELANDER, T
中科院分区：
文献类型：
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作者：
EKHOLM, R;EDLUND, Y;ZELANDER, T
外分泌胰腺的中央腺泡细胞、肾间管细胞和小叶内管细胞表现出明显的超微结构相似性。所有三种类型的特点是细胞质中含有很少的质内网，相对较少的线粒体，适度的高尔基体和相当数量的精细原纤维。顶端细胞表面有微绒毛，细胞核圆形或卵圆形，边缘有凹痕。明显的偏差只存在于顶细胞表面的结构上。在小叶内导管的表面经常有水泡，可达到相当大的尺寸。这种小泡在肾间管中更小、更少，在中央腺泡细胞中偶见。考虑到这三种细胞之间唯一的本质区别是顶端气泡的数量和大小逐渐增加，作者倾向于认为这三种细胞是同源的。讨论了导管细胞的超微结构与它们作为胰液液体和电解质含量提供者的可能作用的关系。
The centro-acinar cells, intercalary duct cells, and intralobular duct cells of the exocrine pancreas exhibit marked ultrastructural similarities. All 3 types are characterized by a cytoplasm containing very little endo-plasmic reticulum, comparatively few, small mitochondria, a modest Golgi apparatus and considerable amounts of delicate fibrils. The apical cell surface has microvilli and the nucleus is round or oval with marginal indentations. Distinct deviations exist only with respect to the configuration of the apical cell surface. In the intralobular ducts this surface very often has blebs which can attain considerable dimensions. Such blebs are much smaller and fewer in the intercalary ducts and they were but occasionally observed in the centroacinar cells. Considering that the sole essential difference between the 3 cells is the progressively increasing number and size of apical blebs the authors are inclined to believe that the cells are homologous. The ultrastructure of the duct cells is discussed in relation to their possible role as provider of fluid and electrolyte content of the pancreatic juice.