Stunting and soil-transmitted-helminth infections among school-age pupils in rural areas of southern China
Stunting and soil-transmitted-helminth infections among school-age pupils in rural areas of southern China
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DOI：
10.1186/1756-3305-3-97
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发表时间：
2010-10-13
影响因子：
3.2
通讯作者：
Lin, Shao-Xiong
中科院分区：
文献类型：
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作者：
Shang, Yu;Tang, Lin-Hua;Lin, Shao-Xiong
背景：发育迟缓和土源性蠕虫（STH）感染，包括蛔虫病、鞭虫病和钩虫病，仍然是发展中国家学龄学生的主要公共卫生问题。本研究的目的是确定中国南方农村地区儿童发育迟缓的患病率及其与三种主要土源性蠕虫 (STH) 的关系。本研究还旨在确定发育迟缓的危险因素，为今后该领域的研究提供预防和控制发育迟缓和STH感染的指导。结果：2009年9月至11月，对STH患病率较高的广西自治区和海南省贫困农村地区进行了横断面调查。调查对象来自15所小学。所有年龄在 9 至 12 岁之间（平均年龄 11.2 +/- 3.2 岁）、三至六年级的学龄学生都参加了这项研究。研究内容包括问卷调查、体格检查和实验室方法（粪便检查三大STH感染虫卵，贫血检查进行血红蛋白测定）。最终有1031名适龄学生参与了调查。结果显示，根据世界卫生组织儿童生长标准（2007 年），发育迟缓（HAZ < 2SD）的总体患病率为 25.6%。根据Logistic回归分析，发育迟缓的危险因素为：（1）STH中度至重度感染（OR = 1.93；95% CI：1.19，3.11）； (2)贫血(OR = 3.26; 95% CI: 2.02,5.27); (3)母亲受教育程度(OR=2.13;95%CI:1.39,3.25)。重大STH感染总体患病率为36.7%，STH中重度感染率为16.7%。蛔虫病、鞭虫病、钩虫病和混合感染的总体患病率分别为18.5%、11.2%、14.7%和9.1%。贫血儿童（HB<12g/dl）的患病率为13.1%。结论：本研究表明，研究人群中发育迟缓的患病率较高，STH感染是发育迟缓的重要危险因素之一，其中中重度感染是发育迟缓的主要预测因素。因此，整个小学年龄段都需要采取额外的干预措施，例如促进驱虫治疗、加强健康教育以及改善个人卫生和环境卫生，以减少该人群的发育迟缓。
Background: Stunting and soil-transmitted helminth (STH) infections including ascariasis, trichuriasis and hookworm remain major public health problems in school-age pupils in developing countries. The objectives of this study were to determine the prevalence of stunting for children and its association with three major soil-transmitted helminths (STH) in rural areas of southern China. The study also aims to determine risk factors for stunting and to provide guidance on the prevention and control of stunting and STH infections for future studies in this field.Results: A cross-sectional survey was carried out in the poor rural areas in Guangxi Autonomous Regional and Hainan Province where STH prevalence was higher between September and November 2009. Pupils were from 15 primary schools. All the school-age pupils aged between 9 and 12 years old (mean age 11.2 +/- 3.2 years), from grades three to six took part in this study. Study contents include questionnaire surveys, physical examination and laboratory methods (stool checking for eggs of three major STH infections and haemoglobin determination was performed for the anaemia test). Finally 1031 school-age pupils took part in survey. The results showed that the overall prevalence of stunting (HAZ < 2SD) was 25.6%, based on the WHO Child Growth Standards (2007). Risk factors for stunting based on logistic regression analyses were: (1) STH moderate-to-heavy intensity infections (OR = 1.93; 95% CI: 1.19,3.11); (2) anaemia (OR = 3.26; 95% CI: 2.02,5.27); (3) education level of mother (OR = 2.13; 95% CI: 1.39,3.25). The overall prevalence of major STH infections was 36.7%, STH moderate-to-heavy intensity infections was 16.7%. The overall prevalence of ascariasis, trichuriasis, hookworm and co-infection were 18.5%, 11.2%, 14.7% and 9.1% respectively. The prevalence of anaemic children (HB < 12 g/dl) was 13.1%.Conclusion: The present study showed that stunting was highly prevalent among the study population and STH infection is one of the important risk factors for stunting, with moderate-to-heavy intensity infections being the main predictor of stunting. Hence, additional interventions measures such as to promote de-worming treatment, to enhance health education and to improve hygiene and sanitation in order to reduce stunting in this population, are needed throughout the primary school age group.