A preliminary trial of Twelve-Step Facilitation and acceptance and commitment therapy with polysubstance-abusing methadone-maintained opiate addicts
A preliminary trial of Twelve-Step Facilitation and acceptance and commitment therapy with polysubstance-abusing methadone-maintained opiate addicts
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DOI：
10.1016/s0005-7894(04)80014-5
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发表时间：
2004-09-01
期刊：
影响因子：
3.7
通讯作者：
Gregg, J
中科院分区：
文献类型：
--
作者：
Hayes, SC;Wilson, KG;Gregg, J
本研究比较了美沙酮维持单独美沙酮维持与16周的强化间歇步骤促进（ITSF）或接受和承诺治疗（ACT）在一项初步疗效试验中与美沙酮维持期间继续使用药物的多物质滥用阿片类药物成瘾者。结果表明，ACT的添加与较低的客观评估阿片类药物和总药物使用在随访期间比美沙酮维持单独，并降低主观措施的总药物使用在随访。一项意向治疗分析假设缺失的药物数据表明药物使用，这也为ACT条件下客观评估的总药物使用减少的可靠性提供了支持。ITSF在随访期间减少了总药物使用的客观指标，但在意向治疗分析中没有减少。在所有条件下，大多数调整和心理困扰的措施都有所改善，但没有证据表明这些领域的条件有不同的改善。作为减少严重药物滥用的一种手段，ACT和ITSF都值得进一步探讨。
The present study compared methadone maintenance alone to methadone maintenance in combination with 16 weeks of either Intensive Twelve-Step Facilitation (ITSF) or Acceptance and Commitment Therapy (ACT) in a preliminary efficacy trial with polysubstance-abusing opiate addicts who were continuing to use drugs while on methadone maintenance. Results showed that the addition of ACT was associated with lower objectively assessed opiate and total drug use during follow-up than methadone maintenance alone, and lower subjective measures of total drug use at follow-up. An intent-to-treat analysis which assumed that missing drug data indicated drug use also provided support for the reliability of objectively assessed total drug use decreases in the ACT condition. ITSF reduced objective measures of total drug use during follow-up but not in the intent-to-treat analyses. Most measures of adjustment and psychological distress improved in all conditions, but there was no evidence of differential improvement across conditions in these areas. Both ACT and ITSF merit further exploration as a means of reducing severe drug abuse.