Effectiveness of Meningococcal B Vaccine against Endemic Hypervirulent Neisseria meningitidis W Strain, England.
Effectiveness of Meningococcal B Vaccine against Endemic Hypervirulent Neisseria meningitidis W Strain, England.
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DOI：
10.3201/eid2202.150369
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发表时间：
2016-02
影响因子：
11.8
通讯作者：
Borrow R
中科院分区：
文献类型：
--
作者：
Ladhani SN;Giuliani MM;Biolchi A;Pizza M;Beebeejaun K;Lucidarme J;Findlow J;Ramsay ME;Borrow R
用脑膜炎球菌血清群B疫苗免疫的儿童的血清样本显示出对在英国流行的高毒力脑膜炎奈瑟菌血清群W菌株的有效血清杀菌抗体活性。最近将这种疫苗引入联合王国国家免疫计划也有助于保护婴儿免受这种地方性毒株的侵害。
Serum samples from children immunized with a meningococcal serogroup B vaccine demonstrated potent serum bactericidal antibody activity against the hypervirulent Neisseria meningitidis serogroup W strain circulating in England. The recent introduction of this vaccine into the United Kingdom national immunization program should also help protect infants against this endemic strain.