Systolic dysfunction is a predictor of long term mortality in men but not in women with heart failure

Systolic dysfunction is a predictor of long term mortality in men but not in women with heart failure
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DOI:
10.1016/j.ehj.2003.07.007
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发表时间:
2003-11-01
影响因子:
39.3
通讯作者:
Almendral, J
Almendral, J
中科院分区:
医学1区
文献类型:
--
作者:
Martínez-Sellés, M;Robles, JAG;Almendral, J

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目的是评估可能的性别差异的临床资料和结果的患者住院治疗heartfailure.Methods和结果在1996年期间,共有1065名住院患者确诊心力衰竭,随访数据到2002年。妇女(58%)年龄大得多,高血压和糖尿病患病率较高,缺血性心脏病、慢性肺病和酗酒患病率较低。左心室射血分数(LVEF)正常的患者比例随年龄增长而增加,但在所有年龄组中,女性LVEF正常的患者比例均高于男性。超声心动图检查在女性中较少见:62% vs.71%,P0.3,但LVEF小于或等于0.3的女性预后较好。结论无论LVEF如何,女性和LVEF >0.3的男性的生存率相似,而LVEF严重降低的男性预后较差。(C)2003年由Elsevier Ltd代表欧洲心脏病学会出版。
Aims To evaluate possible gender differences in clinical profile and outcome of patients hospitalised with heart failure.Methods and results During 1996 a total of 1065 hospital in-patients had confirmed heart failure, with follow-up data through 2002. Women (58%) were significantly older, had higher prevalence of hypertension and diabetes, and lower prevalence of ischaemic heart disease, chronic pulmonary disease and alcoholism. The proportion of patients with normal left ventricular ejection fraction (LVEF) increased with age, but in all age groups women had normal LVEF more frequently than men. Echocardiography was performed less frequently in females: 62% vs. 71% in men, P0.3 but women with LVEF less than or equal to0.3 had a better prognosis than their mate counterparts.Conclusions Survival is similar in women irrespective of LVEF and in men with LVEF >0.3 while men with severely depressed LVEF have a worse prognosis. (C) 2003 Published by Elsevier Ltd on behalf of The European Society of Cardiology.