The Contributions of Epidemiology to the Understanding of Childhood Seizures and Epilepsy

The Contributions of Epidemiology to the Understanding of Childhood Seizures and Epilepsy
复制标题

流行病学对理解儿童癫痫发作和癫痫的贡献

DOI:
10.1177/0883073894009002041
复制
发表时间:
1994
影响因子:
1.9
通讯作者:
S. Shinnar
S. Shinnar
中科院分区:
医学4区
文献类型:
--
作者:
A. Berg;S. Shinnar

文献摘要

参考文献

相似文献

直到20世纪60年代,癫痫的研究都是基于三级转诊中心的患者,其中许多人患有难治性癫痫。根据这些早期的研究,癫痫被认为是一种慢性、进行性和不可治愈的疾病。癫痫发作被认为会造成损害,并导致进一步的癫痫发作。癫痫发作儿童的临床管理反映了这些信念。在过去的25到30年里,流行病学研究表明,与这些早期的信念相反,大多数儿童癫痫发作和癫痫的预后是极好的。预后主要取决于潜在的病因,而不是癫痫发作本身。早期研究与后来的流行病学研究在评估癫痫发作预后方面的差异主要是由于早期研究中出现的一些偏倚。这些偏见得到了解释。提供了几个例子,流行病学研究如何大大改变了流行的观点,癫痫发作的预后,并通过这样做,癫痫发作的管理。(J Child Neurol 1994;9(Suppl):2S19-2S26)。
Up through the 1960s, studies of epilepsy were based on patients seen in tertiary referral centers, many of whom had refractory epilepsy. Based on these early studies, epilepsy was believed to be a chronic, progressive, and incurable disorder. Seizures were thought to cause damage and result in further seizures. Clinical management of children with seizures reflected these beliefs. Over the last 25 to 30 years, epidemiologic studies have demonstrated that, contrary to these earlier beliefs, the prognosis of most childhood seizures and epilepsy is excellent. Prognosis is largely determined by the underlying etiology and not the seizures themselves. The differences in the assessment of the prognosis of seizures derived from the earlier studies versus the later epidemiologic studies are largely due to several biases that occurred in the earlier studies. These biases are explained. Several examples are provided of how the epidemiologic studies have greatly altered the prevailing views regarding the prognosis of seizures, and, by doing so, the management of seizures. (J Child Neurol 1994;9(Suppl):2S19-2S26).
儿童癫痫持续状态的发病率和死亡率较低。
DOI: --
发表时间: 1989
期刊: Pediatrics
影响因子: 8
作者:
Maytal,J;Shinnar,S;Moshe,SL;Alvarez,LA
通讯作者: Alvarez,LA
儿童首次无端癫痫发作后癫痫复发的风险:一项前瞻性研究。
DOI: --
发表时间: 1990
期刊: Pediatrics
影响因子: 8
作者:
Shinnar,S;Berg,AT;Moshe,SL;Petix,M;Maytal,J;Kang,H;Goldensohn,ES;Hauser,WA
通讯作者: Hauser,WA
遗传性癫痫发作表达的年龄特异性。
DOI: --
发表时间: 1991
期刊: Epilepsy research. Supplement
影响因子: --
作者:
Shinnar,S;Moshe,SL
通讯作者: Moshe,SL
智力障碍是癫痫持续状态的结果。
DOI: --
发表时间: 1990
期刊: Neurology
影响因子: 9.9
作者:
Dodrill,CB;Wilensky,AJ
通讯作者: Wilensky,AJ