Development and validation of a questionnaire to assess fear of kidney failure following living donation.
Development and validation of a questionnaire to assess fear of kidney failure following living donation.
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制定并验证一份调查问卷，以评估活体捐赠后对肾衰竭的恐惧。
DOI：
10.1111/tri.12299
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发表时间：
2014
期刊：
影响因子：
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通讯作者：
Mandelbrot,DidierA
中科院分区：
文献类型：
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作者：
Rodrigue,JamesR;Fleishman,Aaron;Vishnevsky,Tanya;Whiting,James;Vella,JohnP;Garrison,Krista;Moore,Deonna;Kayler,Liise;Baliga,Prabhakar;Chavin,KennethD;Karp,Seth;Mandelbrot,DidierA
活体肾脏捐赠者（LKDs）现在可能会对肾功能衰竭感到更加焦虑，因为他们只有一个肾脏，第二个肾脏的安全性已经消失了。本横断面研究的目的是开发并实证验证一种自我报告量表，用于评估前lkd患者对肾衰竭的恐惧。参与者是美国5个移植中心过去10年内的364名前lkd患者，以及通过Mechanical Turk招募的219名健康的非供体对照者，他们完成了几份问卷。分析结果显示，该问卷具有单向度因子结构，具有较好的内部一致性（α = 0.88），具有较好的收敛效度。只有13%的前捐赠者报告有中度到高度的肾衰竭恐惧。非白人种族（OR = 2.9，P= 0.01）、与受赠者的遗传关系（OR = 2.46，P= 0.04）和对捐赠体验的低满意度（OR = 0.49，P= 0.002）是对肾衰竭较高恐惧的显著预测因素。我们的结论是，虽然对肾功能衰竭的轻度焦虑是常见的，但对前lkd患者未来肾功能衰竭的高度焦虑并不常见。对肾衰竭的恐惧问卷是可靠的，有效的，并且易于在临床环境中使用。
Living kidney donors (LKDs) may feel more anxious about kidney failure now that they have only one kidney and the security of a second kidney is gone. The aim of this cross‐sectional study was to develop and empirically validate a self‐report scale for assessing fear of kidney failure in former LKDs. Participants were 364 former LKDs within the past 10 years at five US transplant centers and 219 healthy nondonor controls recruited through Mechanical Turk who completed several questionnaires. Analyses revealed a unidimensional factor structure, excellent internal consistency (α = 0.88), and good convergent validity for the Fear of Kidney Failure questionnaire. Only 13% of former donors reported moderate to high fear of kidney failure. Nonwhite race (OR = 2.9,P= 0.01), genetic relationship with the recipient (OR = 2.46,P= 0.04), and low satisfaction with the donation experience (OR = 0.49,P= 0.002) were significant predictors of higher fear of kidney failure. We conclude that while mild anxiety about kidney failure is common, high anxiety about future renal failure among former LKDs is uncommon. The Fear of Kidney Failure questionnaire is reliable, valid, and easy to use in the clinical setting.