Assessment of the skeletal status by MR relaxometry techniques of the lumbar spine: comparison with dual X-ray absorptiometry
Assessment of the skeletal status by MR relaxometry techniques of the lumbar spine: comparison with dual X-ray absorptiometry
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DOI：
10.1016/j.ejrad.2004.01.021
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发表时间：
2004-06-01
影响因子：
3.3
通讯作者：
Gourtsoyiannis, N
中科院分区：
文献类型：
--
作者：
Maris, TG;Damilakis, J;Gourtsoyiannis, N
目的：测量一组绝经后妇女的腰椎 T2*、T2、T2' 和 T1 MR 松弛测量参数，并将其与腰椎骨矿物质密度 (BMD) 进行比较。材料和方法：对 10 1 名绝经后妇女（平均年龄：61.8 +/- 7.1 (1 S.D.) 岁）评估腰椎 T2*、T2、T2' 和 T1 MR 松弛测量参数和 BMD 值；其中 63 名被称为对照受试者（A 组，BMD T 分数大于或等于 -2.5 S.D.），38 名被称为骨质疏松受试者（B 组，BMD T 分数 < -2.5 S.D.）。所有磁共振成像 (MRI) 检查均在 1.5 T 成像系统上进行，使用：(a) 用于 T2* 测量的 2D 单切片多回波（32 个回波）梯度回波 (MEGRE) 序列（TR/TE1/TE32/FA：160/2.7/74.93 ms/25 度），(b) 呼吸门控 2D 单切片多回波（16 个回波）自旋回波 (MESE) 序列（TR/TE1/TE16/FA：2000-2500/22.5/360 毫秒/90 度）用于 T2 测量，(c) 用于 T1 的 2D 单层多 T1（18 次重复）涡轮快速低角度拍摄（涡轮闪光）序列（TR/TE/T11/T116/FA：11/4.2/10/5000 毫秒/10 度）用于 T1测量。 TT 根据其定义方程计算：(I/T2' = 1/T2* - 1/T2)。使用 DXA 评估腰椎 BMD。结果：所有测量参数在 A 组和 B 组之间均显示出统计学上的显着差异（从 P < 0.05 到
Purpose: To measure lumbar spine T2*, T2, T2' and T1 MR relaxometry parameters and compare them with lumbar spine bone mineral density (BMD) in a group of postmenopausal women. Materials and methods: Lumbar spine T2*, T2, T2' and T1 MR relaxometry parameters and BMD values were assessed in 10 1 postmenopausal women (mean age: 61.8 +/- 7.1 (1 S.D.) years); of them 63 referred to as control subjects (group A, BMD T-scores greater than or equal to -2.5 S.D.) and 38 as osteoporotic (group B, BMD T-scores < -2.5 S.D.). All magnetic resonance imaging (MRI) examinations were performed on an 1.5 T imaging system using: (a) a 2D single slice multi echo (32 echoes) gradient echo (MEGRE) sequence (TR/TE1/TE32/FA: 160/2.7/74.93 ms/25degrees) for the T2* measurement, (b) a respiratory gated 2D single Slice Multi Echo (16 echoes) Spin Echo (MESE) sequence (TR/TE1/TE16/FA: 2000-2500/22.5/360 ms/90degrees) for the T2 measurement and (c) a 2D single slice multi T1 (18 repeats) turbo Fast Low Angle Shot (turbo FLASH) sequence (TR/TE/T11/T116/FA: 11/4.2/10/5000 ms/10degrees) for the T1 measurement. TT was calculated from its definition equation: (I/T2' = 1/T2* - 1/T2). Lumbar spine BMD was assessed using DXA. Results: All measured parameters showed statistically significant differences between groups A and B (from P < 0.05 to