Persistently high prevalence and unrecognized HIV infection among men who have sex with men in Baltimore: the BESURE study.
Persistently high prevalence and unrecognized HIV infection among men who have sex with men in Baltimore: the BESURE study.
复制标题
DOI：
10.1097/qai.0b013e318211b41e
复制
发表时间：
2011-05-01
期刊：
影响因子：
--
通讯作者：
Holtgrave DR
中科院分区：
文献类型：
--
作者：
German D;Sifakis F;Maulsby C;Towe VL;Flynn CP;Latkin CA;Celentano DD;Hauck H;Holtgrave DR
鉴于巴尔的摩男同性恋者中艾滋病毒的高发病率，我们研究了与艾滋病毒流行和未识别的艾滋病毒感染巴尔的摩男同性恋者在两个时间点的特征。2004-2005年和2008年在男男性接触者确定的地点对巴尔的摩成年男性进行横断面行为调查和艾滋病毒检测。MSM被定义为在过去一年中与男性伴侣发生性关系。双变量和向后逐步回归确定了与艾滋病毒和未识别的感染相关的特征。2004-2005年的艾滋病毒感染率为37.7%（n=645），2008年为37.5%（n=448），黑人男男性行为者中分别为51.4%和44.7%，非西班牙裔白色男男性行为者中分别为12.9%和18.3%。与非西班牙裔白色MSM相比，黑人MSM为4.0倍（95% C.I.：2004-2005年，艾滋病毒抗体阳性的可能性增加了2.3，7.0倍，艾滋病毒抗体阳性的可能性增加了2.5倍（95% CI：1.5，4.0）在2008年更有可能。2004-2005年未被确认的艾滋病毒感染率总体为58.4%，2008年为74.4%，黑人男男性行为者为63.8%和76.9%，非西班牙裔白色男男性行为者为15.4%和47.4%。在调整后的模型中，未被识别的感染与少数民族/种族，年龄较小，2004-5年没有前一年的医生就诊以及2008年的年龄较小，没有前一年的医生就诊显著相关。高艾滋病毒感染率和巴尔的摩男男性接触者，特别是有色人种和年轻男子中未被识别的艾滋病毒感染率很高，需要公共和私营部门紧急关注，并加强预防反应。
Given high rates of HIV among Baltimore MSM, we examined characteristics associated with HIV prevalence and unrecognized HIV infection among Baltimore MSM at two time points. Cross-sectional behavioral surveys and HIV testing in 2004–2005 and 2008 using venue-based sampling among adult Baltimore men at MSM-identified locations. MSM was defined as sex with a male partner in the past year. Bivariate and backwards stepwise regression identified characteristics associated with HIV and unrecognized infection. HIV prevalence was 37.7% overall in 2004–2005 (n=645) and 37.5% in 2008 (n=448), 51.4% and 44.7% among Black MSM, and 12.9% and 18.3% among non-Hispanic White MSM. Compared to non-Hispanic White MSM, Black MSM were 4.0 times (95% C.I.: 2.3, 7.0) more likely to be HIV-positive in 2004–2005 and 2.5 times (95% C.I.: 1.5, 4.0) more likely in 2008. Prevalence of unrecognized HIV infection was 58.4% overall in 2004–2005 and 74.4% in 2008, 63.8% and 76.9% among Black MSM, and 15.4% and 47.4% among non-Hispanic White MSM. In adjusted models, unrecognized infection was significantly associated with minority race/ethnicity, younger age, and no prior year doctor visits in 2004–5 and with younger age and no prior year doctor visits in 2008. High rates of HIV infection and substantial rates of unrecognized HIV infection among Baltimore MSM, particularly men of color and young men, require urgent public and private sector attention and increased prevention response.