Lipid-Membrane-Incorporated Hydrophobic Photochromic Molecules Prepared by the Exchange Method Using Cyclodextrins
Lipid-Membrane-Incorporated Hydrophobic Photochromic Molecules Prepared by the Exchange Method Using Cyclodextrins
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环糊精交换法制备脂膜结合疏水光致变色分子
DOI：
10.1039/c5ob00240k
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
K. Yasuhara
中科院分区：
文献类型：
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作者：
A. Ikeda;S. Hino;K. Ashizawa;K. Sugikawa;J. Kikuchi;M. Tsukamoto;K. Yasuhara
结果发现，交换法制备的脂质膜纳入客体分子不仅适用于富勒烯，但也适用于其他疏水分子，如偶氮苯和芪。这种方法的优点是，长期稳定性的脂质膜纳入偶氮苯溶液和[二苯乙烯]/[脂质]的最大比例高于由经典的方法，我们称之为“预混法”制备的。这些光致变色客体分子在脂质膜中的光异构化维持了脂质体的形态。
It was found that the exchange method for the preparation of lipid-membrane-incorporated guest molecules was applicable not only to fullerenes but also to other hydrophobic molecules such as azobenzene and stilbene. The advantages of this method are that the long-term stability of the lipid-membrane-incorporated azobenzene solution and the maximum ratio of [stilbene]/[lipid] were higher than those prepared by the classical method, which we call the ‘premixing method’. Photoisomerisations of these photochromic guest molecules in the lipid membranes maintained the morphology of liposomes.