The significance, assessment, and management of nonrestorative sleep in fibromyalgia syndrome

The significance, assessment, and management of nonrestorative sleep in fibromyalgia syndrome
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DOI:
10.1017/s1092852900026808
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发表时间:
2008-03-01
期刊:
影响因子:
3.3
通讯作者:
Moldofsky, Harvey
Moldofsky, Harvey
中科院分区:
医学3区
文献类型:
--
作者:
Moldofsky, Harvey

文献摘要

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患有纤维肌痛综合征(FMS)的人会经历睡眠不佳,疼痛,过敏,认知和情绪困难。虽然没有特定的致病因素或生物制剂是已知的所有功能的FMS和这些相关的诊断,全身性超敏反应的身体被认为是受干扰的中枢神经系统(CNS)功能。这种CNS紊乱是睡眠-觉醒脑固有的,其中所有这些疾病的共同症状元素是睡眠质量差、非特异性疼痛、疲劳和在没有已知疾病病理学的情况下的心理困扰。
People with fibromyalgia syndrome (FMS) experience unrefreshing sleep, aches, hypersensitivity, and cognitive and emotional difficulties. Although no specific causative factor or biological agent is known to account for all of the features of FMS and these related diagnoses, the generalized hypersensitivity of the body is considered to be affected by disturbances in central nervous system (CNS) functions. Such CNS disturbances are intrinsic to the sleeping-waking brain, where the common symptom elements in all these illnesses are poor quality of sleep, nonspecific pain, fatigue, and psychological distress in the absence of known disease pathology.