FoxO3a eggs on fertility and aging
FoxO3a eggs on fertility and aging
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DOI：
10.1016/j.molmed.2003.09.003
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发表时间：
2003-11-01
影响因子：
13.6
通讯作者：
Burgering, BMT
中科院分区：
文献类型：
--
作者：
Brenkman, AB;Burgering, BMT
FoxO转录因子（FoxO1a、3a和4）包括叉头转录因子家族的一个小的亚家族。越来越多的研究提供了遗传学证据，表明叉头转录因子控制胚胎发生中的关键步骤，对所有胚层和器官的发育至关重要（最近的综述，见参考文献[1]）。Castrillon等人[2]最近的一项研究增加了FoxO3a在控制卵泡发育中的功能。
The FoxO transcription factors (FoxO1a, 3a and 4) comprise a small subfamily of the Forkhead transcription factor family. An increasing number of studies has provided genetic evidence showing that Forkhead transcription factors control crucial steps in embryogenesis and are essential for the development of all germ layers and organs (for a recent review, see Ref. [1]). A recent study by Castrillon et al. [2] has now added a function for FoxO3a in the control of follicular development.