Meniere's disease: effects of glycerol on tasks involving temporal processing.

Meniere's disease: effects of glycerol on tasks involving temporal processing.
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梅尼埃病:甘油对涉及时间处理的任务的影响。

DOI:
10.1159/000076002
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发表时间:
2004
影响因子:
1.6
通讯作者:
Pillsbury,HaroldC
Pillsbury,HaroldC
中科院分区:
医学3区
文献类型:
--
作者:
Chung,BrianJ;Hall,JosephW;Buss,Emily;Grose,JohnH;Pillsbury,HaroldC

文献摘要

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The present study examined the effect of glycerol ingestion on aspects of auditory performance in subjects having Ménière’s disease. It was hypothesized that Ménière’s disease may be associated with abnormal firing in the auditory nerve and that this should result in a decreased ability to code the auditory temporal fine structure. Psychoacoustical measures of interaural time discrimination and quasi frequency modulation rate discrimination were used as measures of temporal coding, and performance on these tasks was examined both before and after glycerol ingestion. Pre-and postglycerol measures of speech recognition and audiometric thresholds were also obtained. In agreement with previous results, glycerol-related changes in audiometric thresholds were modest or absent, but improvements in speech recognition were relatively reliable. Improvements in interaural time discrimination and quasi frequency modulation rate discrimination were also observed. The results provide limited support for the hypothesis that Ménière’s disease may be associated with a reduced ability to code the temporal fine structure of sound.