Computerized tomography to define CNS involvement in congenital cytomegalovirus infection.
Computerized tomography to define CNS involvement in congenital cytomegalovirus infection.
复制标题
计算机断层扫描以确定先天性巨细胞病毒感染中枢神经系统的参与。
DOI：
10.1001/archpedi.1980.02130200063020
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发表时间：
1980
影响因子：
--
通讯作者：
L. C. Foley
中科院分区：
文献类型：
--
作者：
B. Anders;B. Lauer;L. C. Foley
先天性巨细胞病毒（CMV）感染最严重的后遗症包括中枢神经系统。然而，预测先天性巨细胞病毒新生儿的神经预后可能是困难的，除非在出生时严重的中枢神经系统损伤已经很明显。一些与巨细胞病毒感染相关的宫内发育迟缓、肝脾肿大和其他症状严重的患儿智力发育正常，没有可检测到的神经功能缺陷。神经学评估通常包括仔细的神经学检查和颅骨x线检查以发现钙化。我们描述了一个新生儿证实先天性巨细胞病毒感染，他有正常的神经检查和正常的头骨x线片；计算机断层扫描（CT）能更准确地显示中枢神经系统受累的严重程度。病例报告。一位28岁的母亲生下了一个足月女婴，她的梅毒检测呈阴性，风疹滴度呈阳性。婴儿体重2110克，阿普加评分为7分
The most serious sequelae of congenital cytomegalovirus (CMV) infection involve the CNS. However, predicting the neurological outcome of a neonate with congenital CMV may be difficult unless severe CNS damage is already obvious at birth. Some severely affected babies with intrauterine growth retardation, hepatosplenomegaly, and other stigmata associated with CMV infection have normal intellectual development without detectable neurological deficits.1Neurological evaluation usually consists of a careful neurological examination and a roentgenogram of the skull to detect calcifications. We describe a newborn with proven congenital CMV infection who had a normal neurological examination and a normal roentgenogram of the skull; computerized tomography (CT) gave a more accurate picture of the severity of CNS involvement. Report of a Case.—A full-term baby girl was born to a 28-year-old-mother who had a negative test for syphilis and a positive rubella titer. The baby weighted 2,110 g and had and Apgar score of 7 at