Four Carbapenem-Resistant Gram-Negative Species Carrying Distinct Carbapenemases in a Single Patient
Four Carbapenem-Resistant Gram-Negative Species Carrying Distinct Carbapenemases in a Single Patient
复制标题
DOI：
10.1128/jcm.03623-14
复制
发表时间：
2014-12
影响因子：
9.4
通讯作者：
B. Ding;F. Hu;Yang Yang-Yang;Q. Guo;Jinwei Huang;Minggui Wang
中科院分区：
文献类型：
--
作者：
B. Ding;F. Hu;Yang Yang-Yang;Q. Guo;Jinwei Huang;Minggui Wang
摘要 从一名患者体内分离出耐碳青霉烯类大肠杆菌、肺炎克雷伯菌、产气肠杆菌和鲍曼不动杆菌，每种菌株产生不同的碳青霉烯酶（分别为 NDM-1、KPC-2、IMP 和 OXA-23）。一个月前，在产生 NDM-1 的大肠杆菌菌株之前出现了克隆相关的碳青霉烯类敏感菌株，这表明 bla NDM-1 在体内获得。
ABSTRACT Carbapenem-resistant Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii were isolated from a single patient, each producing different carbapenemases (NDM-1, KPC-2, IMP, and OXA-23, respectively). The NDM-1-producing E. coli strain was preceded by a clonally related carbapenem-susceptible strain a month earlier, suggesting in vivo acquisition of bla NDM-1.