Prenatal MR imaging of congenital diaphragmatic hernias: association of MR fetal lung volume with the need for postnatal prosthetic patch repair
Prenatal MR imaging of congenital diaphragmatic hernias: association of MR fetal lung volume with the need for postnatal prosthetic patch repair
复制标题
DOI：
10.1007/s00330-014-3410-8
复制
发表时间：
2015-01-01
影响因子：
5.9
通讯作者：
Neff, K. Wolfgang
中科院分区：
文献类型：
--
作者：
Hagelstein, Claudia;Zahn, Katrin;Neff, K. Wolfgang
目的探讨先天性膈疝（CDH）新生儿出生后是否需要人工补片修补肺缺损与产前测量的磁共振胎儿肺容积（o/e MR-FLV）的相关性。Logistic回归分析被用来评估与产后补片repair.Results 77%（77%）的CDH患者（190/247）需要修复补片修复和缺陷主要关闭23%（57/247）的个人O/E MR-FLV的预后价值。需要补片的患者的o/e MR-FLV（27.7 +/-10.2%）显著低于初次修复患者（40.8 +/-13.8%，p
Objective To assess whether the need for postnatal prosthetic patch repair of the diaphragmatic defect in neonates with a congenital diaphragmatic hernia (CDH) is associated with the antenatal measured observed-to-expected magnetic resonance fetal lung volume (o/e MR-FLV).Methods The o/e MR-FLV was calculated in 247 fetuses with isolated CDH. Logistic regression analysis was used to assess the prognostic value of the individual o/e MR-FLV for association with the need for postnatal patch repair.Results Seventy-seven percent (77 %) of patients with a CDH (190/247) required prosthetic patch repair and the defect was closed primarily in 23 % (57/247). Patients requiring a patch had a significantly lower o/e MR-FLV (27.7 +/- 10.2 %) than patients with primary repair (40.8 +/- 13.8 %, p