Increased incidence of vibriosis in Maryland, U.S.A., 2006-2019.
Increased incidence of vibriosis in Maryland, U.S.A., 2006-2019.
复制标题
2006 年至 2019 年美国马里兰州弧菌病发病率增加。
DOI：
10.1016/j.envres.2023.117940
复制
发表时间：
2024
影响因子：
8.3
通讯作者：
Sapkota,AmyR
中科院分区：
文献类型：
--
作者：
Morgado,MicheleE;Brumfield,KyleD;Mitchell,Clifford;Boyle,MichelleM;Colwell,RitaR;Sapkota,AmyR
研究背景弧菌属天然存在于中等盐度的温水中。在美国，非霍乱弧菌（弧菌病）的感染每年估计导致80，000例疾病和100例死亡。与气候相关的水生生态系统环境参数的变化在很大程度上促进了弧菌的生长，全球范围内报道了弧菌病发病率的增加。然而，美国东北部的弧菌病趋势（例如，方法从COVIS数据库中获得马里兰州2006-2019年611例弧菌病病例数据。使用美国人口普查局对马里兰州人口的估计计算发病率。Logistic回归模型，包括地区，年龄组，种族，性别，职业和暴露类型，被用来估计住院的可能性。结果比较2006-2012年和2013-2019年期间，有一个39%（p= 0.01）的平均年发病率增加（每10万人口）的弧菌病，与V。创伤感染增加最多（53%，p = 0.01），其次是V.副溶血性链球菌（47%，p = 0.05）。住院人数增加了58%（p= 0.01）。自2010年以来，报告了更多住院时间≥10天的弧菌病病例。从上东部海岸地区和那些年龄超过65岁的患者更有可能（OR = 6.8和12.2）住院相比，其他patients.ConclusionsLong-term increases in Vibrioinfections，notablyV。创伤感染，正在发生在马里兰州。这一趋势，沿着住院率和平均住院时间的增加，强调需要提高公众意识、水监测、收获后海产品干预措施和环境预测能力。
BackgroundVibriospp. naturally occur in warm water with moderate salinity. Infections with non-choleraVibrio(vibriosis) cause an estimated 80,000 illnesses and 100 fatalities each year in the United States. Climate associated changes to environmental parameters in aquatic ecosystems are largely promotingVibriogrowth, and increased incidence of vibriosis is being reported globally. However, vibriosis trends in the northeastern U.S. (e.g., Maryland) have not been evaluated since 2008.MethodsVibriosis case data for Maryland (2006–2019; n = 611) were obtained from the COVIS database. Incidence rates were calculated using U.S. Census Bureau population estimates for Maryland. A logistic regression model, including region, age group, race, gender, occupation, and exposure type, was used to estimate the likelihood of hospitalization.ResultsComparing the 2006–2012 and 2013–2019 periods, there was a 39% (p= 0.01) increase in the average annual incidence rate (per 100,000 population) of vibriosis, withV. vulnificusinfections seeing the greatest percentage increase (53%,p= 0.01), followed byV. parahaemolyticus(47%,p= 0.05). The number of hospitalizations increased by 58% (p= 0.01). Since 2010, there were more reported vibriosis cases with a hospital duration ≥10 days. Patients from the upper eastern shore region and those over the age of 65 were more likely (OR = 6.8 and 12.2) to be hospitalized compared to other patients.ConclusionsLong-term increases inVibrioinfections, notablyV. vulnificuswound infections, are occurring in Maryland. This trend, along with increased rates in hospitalizations and average hospital durations, underscore the need to improve public awareness, water monitoring, post-harvest seafood interventions, and environmental forecasting ability.