Vegetables, fruits, and risk of colorectal cancer: A case-control study from Uruguay

Vegetables, fruits, and risk of colorectal cancer: A case-control study from Uruguay
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DOI:
10.1080/01635589609514453
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发表时间:
1996-01-01
影响因子:
2.9
通讯作者:
Ronco, A
Ronco, A
中科院分区:
医学4区
文献类型:
--
作者:
DeneoPellegrini, H;DeStefani, E;Ronco, A

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为了研究蔬菜和水果摄入量是否会改变结直肠癌的风险,在乌拉圭进行了一项病例对照研究。通过使用61种食物的食物频率问卷详细评估饮食模式(对于诊断或症状发生前的病例),从而计算总能量摄入量。通过回归分析计算养分残留量。调整潜在混杂因素(包括体重指数、总能量和总酒精摄入量)后,观察到蔬菜总摄入量、水果总摄入量以及生菜、苹果和香蕉摄入量的风险降低。与第一个三分位数相比,第三个三分位数中香蕉摄入量(比值比0.28:95%置信水平0.16-0.50)的保护作用最强。
To examine whether vegetable and fruit intake modify colorectal cancer risk, a case-control study was conducted in Uruguay. Dietary patterns were assessed in detail (for cases before diagnosis or symptoms occurred) by use of a food frequency questionnaire on 61 food items, which allowed the calculation of total energy intake. Nutrient residuals were calculated through regression analysis. After adjustment for potential confounders (which included body mass index total energy, and total alcohol intake), a reduction in risk for total vegetable intake, total fruit intake, and lettuce, apple, and banana consumption was observed. The strongest protection was observed for banana intake (odds ratio 0.28: 95% confidence level 0.16-0.50) for consumption in the third tertile compared with the first.