Routing of transported materials in the dorsal root and nerve fiber branches of the dorsal root ganglion.
Routing of transported materials in the dorsal root and nerve fiber branches of the dorsal root ganglion.
复制标题
运输物质在背根和背根神经节的神经纤维分支中的路由。
DOI：
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发表时间：
1978
期刊：
影响因子：
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通讯作者：
V. McAdoo
中科院分区：
文献类型：
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作者：
Sidney Ochs;J. Erdman;R. Jersild;V. McAdoo
在用3 H-亮氨酸注射L7背根神经节后，与神经元的背根纤维分支相比，快速轴浆运输沿着进入坐骨神经的感觉纤维分支运载了约3- 5倍多的标记材料。从猫和猴的腰第七背根神经节两侧取的冷冻替代制剂显示，与背根纤维分支相比，这些神经元的感觉神经纤维分支的神经纤维直径的直方图几乎没有差异。在电子显微镜制备中，在宽范围的纤维直径内，在背根和感觉神经纤维分支中发现了类似密度的微管和神经丝。在没有解剖差异的纤维占不对称流出，功能的解释的基础上的运输丝模型。
After injection of the L7 dorsal root ganglion with 3H-leucine, fast axoplasmic transport carries some 3--5 x more labeled materials down the sensory fibers branches entering the sciatic nerve as compared to the dorsal root fiber branches of the neurons. Freeze-substitution preparations taken from the two sides of the lumbar seventh dorsal root ganglia of cats and monkeys showed little difference in the histograms of nerve fiber diameters of the sensory nerve fiber branch of these neurons as compared to the dorsal root fiber branches. A similar density of microtubules and of neurofilaments in the dorsal root and sensory nerve fiber branches over a wide range of fiber diameters was found in electron micrograph preparations. In the absence of an anatomical difference in the fibers to account for the asymmetrical outflow, a functional explanation based on the transport filament model was advanced.