Lung Cancer and Occupation: A New Zealand Cancer Registry-Based Case-Control Study
Lung Cancer and Occupation: A New Zealand Cancer Registry-Based Case-Control Study
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DOI：
10.1002/ajim.20906
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发表时间：
2011-02-01
影响因子：
3.5
通讯作者：
Pearce, Neil
中科院分区：
文献类型：
--
作者：
Corbin, Marine;McLean, David;Pearce, Neil
有许多已证实和怀疑的职业性原因导致肺白斑；随着时间的推移，随着吸烟率的下降，这将变得相对更重要。方法对2007-2008年新西兰癌症登记处登记的457例20-75岁患者和792例人口对照进行访谈。我们收集了有关人口统计细节、潜在混杂因素和就业历史的信息。使用经性别调整的逻辑回归对关联进行估计；年龄，种族，吸烟和社会经济地位。结果在先验感兴趣的职业中，观察到锯木厂、木板和相关木材加工厂操作员（OR为4.63;95% CI 1.05-20.29）、屠夫（OR为8.77,95% CI 1.06-72.55）、橡胶和塑料制品机械操作员（OR为4.27;1.16-15.66）、重型卡车司机（OR为2.24;1.19-4.21）和石油、煤炭、化工和相关产品制造工人（OR为1.80;1.11-2.90）的比值比升高；伐木工人（4.67;0.81-27.03）、焊工和火焰切割工（2.50;0.86-7.25）、压力机（5.74;0.96-34.42）和电气和电子设备装配工（3.61;0.96-13.57）的风险也未显著升高。一些非先验兴趣的职业和行业也显示出增加的风险，包括护理助理专业人员（5.45;2.29-12.99），注册护士（7.95;3.10-20.42），护理员（3.47;1.40-8.59），工厂和机器操作员和装配工（1.61;1.20-2.16），固定机器操作员和装配工（1.67;1.22-2.28），食品和相关产品加工机器操作员（1.98;1.23-3.19），劳动者和相关初级服务工作者(1.45；1.05-2.00)、制造业（1.34;1.02-1.77）、汽车零售业（3.08;1.36-6.94）和公路货运（3.02;1.45-6.27）。某些职业和行业增加了新西兰的肺癌风险，包括木工、金属工人、肉类工人、纺织工人和司机。点。中华医学杂志，2011,44(4):389 - 391。(C) 2010 Wiley-Liss, Inc。
Background There are many proven and suspected occupational causes of lung calico; which will become relatively more important over time, as smoking prevalence decreases.Methods We interviewed 457 cases aged 20-75 years notified to the New Zealand Cancer Registry during 2007-2008, and 792 population controls. We collected information on demographic details, potential confounders, and employment history. Associations were estimated using logistic regression adjusted for gender; age, ethnicity, smoking, and socio-economic status.Results Among occupations of a priori interest, elevated odds ratios (ORs) were observed for sawmill, wood panel and related wood-processing plant operators (OR 4.63; 95% CI 1.05-20.29), butchers (OR 8.77, 95% CI 1.06-72.55), rubber and plastics products machine operators (4.27; 1.16-15.66), heavy truck drivers (2.24; 1.19-4.21) and workers in petroleum, coal, chemical and associated product manufacturing (1.80; 1.11-2.90); non-significantly elevated risks were also observed for loggers (4.67; 0.81-27.03), welders and flame-cutters (2.50; 0.86-7.25), pressers (5.74; 0.96-34.42), and electric and electronic equipment assemblers (3.61; 0.96-13.57). Several occupations and industries not of a priori interest also showed increased risks, including nursing associate professionals (5.45; 2.29-12.99), enrolled nurses (7.95; 3.10-20.42), care givers (3.47; 1.40-8.59), plant and machine operators and assemblers (1.61; 1.20-2.16), stationary machine operators and assemblers (1.67; 1.22-2.28), food and related products processing machine operators (1.98; 1.23-3.19), laborers and related elementary service workers (1.45; 1.05-2.00), manufacturing (1.34; 1.02-1.77), car retailing (3.08; 1.36-6.94), and road freight transport (3.02; 1.45-6.27).Conclusions Certain occupations and industries have increased lung cancer risks in New Zealand, including wood workers, metal workers, meat workers, textile workers and drivers. Am. J. Ind. Med. 54:89-101, 2011. (C) 2010 Wiley-Liss, Inc.