Surface-enhanced unfolding of collapsed polymers in shear flow

Surface-enhanced unfolding of collapsed polymers in shear flow
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DOI:
10.1209/0295-5075/80/18001
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发表时间:
2007-01-01
期刊:
EPL
影响因子:
1.8
通讯作者:
Netz, R. R.
Netz, R. R.
中科院分区:
物理与天体物理4区
文献类型:
--
作者:
Alexander-Katz, A.;Netz, R. R.

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利用流体力学模拟,研究了在平面壁面附近的聚合物在剪切作用下的展开。在一个明确定义的阈值剪切速率伽玛*以上,球变得不稳定,并显示拉伸-再折叠事件。随着离地表距离的减小,临界剪切速率gamma*减小,这在标度分析中是合理的,即由于地表引起的球体旋转和动变慢,流体动应力增加。我们的结果与蛋白质辅助的毛细血管凝血有关。中国人民解放军版权所有,2007。
Using hydrodynamic simulations we study the shear-induced unfolding of a collapsed polymer near a planar wall. Above a well- de. fined threshold shear rate gamma*, the globule becomes unstable and displays stretching-refolding events. With decreasing distance from the surface, the critical shear rate gamma* goes down, which is rationalized within a scaling analysis in terms of increased hydrodynamic stress due to a surface-induced slowing-down of globule rotation and translation. Our results are relevant for protein-assisted blood clotting in capillary vessels. Copyright (C) EPLA, 2007.