GenePaint.org: an atlas of gene expression patterns in the mouse embryo
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
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DOI：
10.1093/nar/gkh029
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发表时间：
2004-01-01
影响因子：
14.9
通讯作者：
Eichele, G
中科院分区：
文献类型：
--
作者：
Visel, A;Thaller, C;Eichele, G
高通量仪器最近开发的RNA原位杂交，以确定组织切片上的基因表达模式。由此产生的基因表达模式的图像，主要是E14.5小鼠胚胎，可在http://www.genepaint.org上向公众提供。此外，模式和强度的表达，在类似于100个不同的胚胎组织进行了注释，并可以搜索使用标准化目录的解剖结构。一个虚拟的显微镜工具，缩放图像服务器，在GenePaint.org上实现，并允许交互式缩放和平移超过15000个高分辨率图像。
High-throughput instruments were recently developed to determine gene expression patterns on tissue sections by RNA in situ hybridization. The resulting images of gene expression patterns, chiefly of E14.5 mouse embryos, are accessible to the public at http://www.genepaint.org. This relational database is searchable for gene identifiers and RNA probe sequences. Moreover, patterns and intensity of expression in similar to100 different embryonic tissues are annotated and can be searched using a standardized catalog of anatomical structures. A virtual microscope tool, the Zoom Image Server, was implemented in GenePaint.org and permits interactive zooming and panning across similar to15 000 high-resolution images.