The achaete‐scute complex is expressed in neurogenic regions of Drosophila embryos
The achaete‐scute complex is expressed in neurogenic regions of Drosophila embryos
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DOI：
10.1002/j.1460-2075.1987.tb02474.x
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发表时间：
1987-07
期刊：
影响因子：
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通讯作者：
S. Romani;S. Campuzano;J. Modolell
中科院分区：
文献类型：
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作者：
S. Romani;S. Campuzano;J. Modolell
黑腹果蝇的无毛鳞片基因复合体（AS-C）参与胚胎中枢神经系统以及幼虫和成虫表皮感觉器官的发育。我们确定了在复合体的achaete、scute α和致死scute区域编码的三种转录物的胚胎空间分布。RNA主要存在于胚盘/早期原肠胚和胚带缩短阶段之间。其表达模式复杂且进化迅速，影响大多数或所有已知的神经原性区域。基因表达先于神经细胞前体的组织学外观并与其同时出现。这些结果支持AS‐C在胚胎神经细胞的决定和早期分化中的作用。
The achaete‐scute gene complex (AS‐C) of Drosophila melanogaster is involved in the development of the embryonic central nervous system and the cuticular sensory organs of both larva and adult. We have determined the embryonic spatial distributions of three transcripts encoded in the achaete, scute α and lethal of scute regions of the complex. The RNAs are present mainly between the blastoderm/early gastrula and the stage of germ band shortening. The patterns of expression are complex and evolve rapidly, affecting most or all of the known neurogenic regions. Gene expression precedes and is concomitant with the histological appearance of precursors of neural cells. These results support a role for the AS‐C in determination and early differentiation of embryonic neural cells.