A Measles Outbreak in an Underimmunized Amish Community in Ohio

A Measles Outbreak in an Underimmunized Amish Community in Ohio
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DOI:
10.1056/nejmoa1602295
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发表时间:
2016-10-06
影响因子:
158.5
通讯作者:
DiOrio, Mary
DiOrio, Mary
中科院分区:
医学1区
文献类型:
--
作者:
Gastanaduy, Paul A.;Budd, Jeremy;DiOrio, Mary

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尽管麻疹在2000年在美国被消灭,但病毒的输入继续导致疫情爆发。我们描述了麻疹爆发的流行病学特征,起源于两名未接种疫苗的阿米什人,他们从菲律宾返回美国时正在潜伏麻疹,并探讨了公共卫生应对措施对限制麻疹传播的影响。2014年,截至2014年7月23日,俄亥俄州9个县共报告了383例麻疹疫情相关病例。病例患者的中位年龄为15岁(范围,
BACKGROUNDAlthough measles was eliminated in the United States in 2000, importations of the virus continue to cause outbreaks. We describe the epidemiologic features of an outbreak of measles that originated from two unvaccinated Amish men in whom measles was incubating at the time of their return to the United States from the Philippines and explore the effect of public health responses on limiting the spread of measles.METHODSWe performed descriptive analyses of data on demographic characteristics, clinical and laboratory evaluations, and vaccination coverage.RESULTSFrom March 24, 2014, through July 23, 2014, a total of 383 outbreak-related cases of measles were reported in nine counties in Ohio. The median age of case patients was 15 years (range,