Highly fluorescent Zn-doped carbon dots as Fenton reaction-based bio-sensors: an integrative experimental-theoretical consideration
Highly fluorescent Zn-doped carbon dots as Fenton reaction-based bio-sensors: an integrative experimental-theoretical consideration
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高荧光锌掺杂碳点作为基于芬顿反应的生物传感器：综合实验理论考虑
DOI：
10.1039/c6nr05434j
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发表时间：
2016-11-07
期刊：
影响因子：
6.7
通讯作者：
Sreeprasad, Theruvakkattil Sreenivasan
中科院分区：
文献类型：
--
作者：
Xu, Quan;Liu, Yao;Sreeprasad, Theruvakkattil Sreenivasan
杂原子掺杂碳点(Cd)具有较高的光致发光量子产率(PLQY)，在化学传感器、生物成像、电子学、光伏等领域具有广泛的应用前景。锌是一种重要的辅助电子传递过程的元素，也是细胞所必需的微量元素，是一种很有前途的硫化镉的金属掺杂剂，可能会导致多功能的硫化镉。在这篇文章中，我们报道了一种一步、高效、水热合成锌掺杂碳点(锌-镉)的方法。通过控制前驱体比例和表面氧化，可以调节锌-硫化镉的PLQY和发光特性。虽然有一些研究报道了金属掺杂的硫化镉具有良好的PLQY，但用本方法制备的锌-硫化镉的PLQY高达32.3%。据我们所知，目前还没有关于简单制备QY超过30%的单金属掺杂Cd的报道。锌-硫化镉的另一个独特属性是高的单分散性和所产生的高度强健的独立于激发的发光，该发光在广泛的pH值范围内稳定。光谱研究表明，锌-硫化镉具有良好的PLQY和发光性能是由于杂原子定向氧化的碳基表面钝化所致。此外，我们开发了一种新型的、灵敏的生物传感器来检测过氧化氢和葡萄糖，利用锌-镉的强大的荧光特性。在最佳条件下，锌镉对过氧化氢和葡萄糖表现出较高的灵敏度和响应范围，线性范围分别为10-80微米和5-100微米，显示了其作为化学传感荧光探针的巨大潜力。
Heteroatom doped carbon dots (CDs), with high photoluminescence quantum yield (PLQY), are of keen interest in various applications such as chemical sensors, bio-imaging, electronics, and photovoltaics. Zinc, an important element assisting the electron-transfer process and an essential trace element for cells, is a promising metal dopant for CDs, which could potentially lead to multifunctional CDs. In this contribution, we report a single-step, high efficiency, hydrothermal method to synthesize Zn-doped carbon dots (Zn-CDs) with a superior PLQY. The PLQY and luminescence characteristic of Zn-CDs can be tuned by controlling the precursor ratio, and the surface oxidation in the CDs. Though a few studies have reported metal doped CDs with good PLQY, the as prepared Zn-Cds in the present method exhibited a PLQY up to 32.3%. To the best of our knowledge, there is no report regarding the facile preparation of single metal-doped CDs with a QY more than 30%. Another unique attribute of the Zn-CDs is the high monodispersity and the resultant highly robust excitation-independent luminescence that is stable over a broad range of pH values. Spectroscopic investigations indicated that the superior PLQY and luminescence of Zn-CDs are due to the heteroatom directed, oxidized carbon-based surface passivation. Furthermore, we developed a novel and sensitive biosensor for the detection of hydrogen peroxide and glucose leveraging the robust fluorescence properties of Zn-CDs. Under optimal conditions, Zn-CDs demonstrated high sensitivity and response to hydrogen peroxide and glucose over a wide range of concentrations, with a linear range of 10-80 mu M and 5-100 mu M, respectively, indicating their great potential as a fluorescent probe for chemical sensing.