Genetic analysis of a complex trait in the Utah Genetic Reference Project: a major locus for PTC taste ability on chromosome 7q and a secondary locus on chromosome 16p
Genetic analysis of a complex trait in the Utah Genetic Reference Project: a major locus for PTC taste ability on chromosome 7q and a secondary locus on chromosome 16p
复制标题
DOI：
10.1007/s00439-003-0911-y
复制
发表时间：
2003-05-01
期刊：
影响因子：
5.3
通讯作者：
Leppert, M
中科院分区：
文献类型：
--
作者：
Drayna, D;Coon, H;Leppert, M
人类品尝苯硫脲（PTC）的能力显示出复杂的遗传。我们获得了PTC品尝能力在267名成员的26个大的三代家庭的一组CEPH家庭的一部分，已被用于遗传作图的定量测量。年龄和性别校正后的得分分布呈双峰性（P
The ability to taste phenylthiocarbamide (PTC) shows complex inheritance in humans. We obtained a quantitative measure of PTC tasting ability in 267 members of 26 large three-generation families that were part of a set of CEPH families that had been used for genetic mapping. Significant bimodality was found for the distribution of age and gender adjusted scores (P