A randomly selected population sample undergoing colonoscopy: prevalence of the irritable bowel syndrome and the impact of selection factors
A randomly selected population sample undergoing colonoscopy: prevalence of the irritable bowel syndrome and the impact of selection factors
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DOI：
10.1097/meg.0000000000000024
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发表时间：
2014-03-01
影响因子：
2.1
通讯作者：
Andreasson, Anna
中科院分区：
文献类型：
--
作者：
Kjellstrom, Lars;Molinder, Herdis;Andreasson, Anna
目的分析肠易激综合征（IBS）症状在普通人群和同意结肠镜检查的随机样本中的流行病学，以及这在多大程度上引入了症状选择偏差。材料和方法随机抽取3347名年龄在18-70岁的瑞典成年人，邮寄有效的腹部症状问卷（ASQ）。通过电话联系应答者（n=2293; 68.5%），其中745人同意结肠镜检查。所有无应答者都通过电话联系；265人被问及7个关键的ASQ问题。结肠镜检查参与者还完成了Rome II模块问卷。结果：在ASQ应答者中，基于ASQ（过去3个月内腹痛和肠道紊乱）的IBS患病率为26.2%[95%置信区间（CI）： 24.4-28.0]，结肠镜检查参与者中为36.6% （95% CI: 33.2-40.1）
ObjectiveTo analyse the epidemiology of irritable bowel syndrome (IBS) symptoms in a random sample of the general population and in a subsample consenting to a colonoscopy, and to what extent this introduces symptom selection bias.Materials and methodsOverall, 3347 randomly selected Swedish adults aged 18-70 years were mailed the validated Abdominal Symptom Questionnaire (ASQ). Responders (n=2293; 68.5%) were contacted by phone, and 745 consented to a colonoscopy. All nonresponders were contacted by phone; 265 were reached and asked seven key ASQ questions. Colonoscopy participants also completed the Rome II Modular Questionnaire.ResultsThe prevalence of IBS on the basis of the mailed ASQ (troublesome abdominal pain and bowel disturbance in the past 3 months) was 26.2% [95% confidence interval (CI): 24.4-28.0] among the ASQ responders and 36.6% (95% CI: 33.2-40.1) among the colonoscopy participants (P