Exaptation of transposable element coding sequences
Exaptation of transposable element coding sequences
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DOI：
10.1016/j.gde.2018.02.011
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发表时间：
2018-04-01
影响因子：
4
通讯作者：
Bureau, Thomas E.
中科院分区：
文献类型：
--
作者：
Joly-Lopez, Zoe;Bureau, Thomas E.
转座因子（te）是一种可移动的遗传因子，曾经被认为仅仅是自私的，但现在被认为是适应的有力媒介。TE促进基因组进化的一种方式是通过TE扩增，在这个过程中，通常通过在基因组中复制而持续存在的TE转化为新的宿主基因，这些基因随后通过赋予表型优势而持续存在。已知外排TE具有多种重要功能，并可能促进间断平衡，但我们对TE外排的过程知之甚少。为了促进我们对TE编码序列如何成为预期的理解，在这里，我们将最近发表的研究结果纳入一个框架和六步模型。
Transposable elements (TEs) are mobile genetic elements that were once perceived as merely selfish, but are now recognized as potent agents of adaptation. One way TEs contribute to genome evolution is through TE exaptation, a process whereby TEs, which usually persist by replicating in the genome, transform into novel host genes, which thereafter persist by conferring phenotypic benefits. Exapted TEs are known to contribute diverse and vital functions, and may facilitate punctuated equilibrium, yet we have little understanding about the process of TE exaptation. In order to facilitate our understanding of how TE coding sequences may become exapted, here we incorporate the findings of recent publications into a framework and six-step model.