Folate and vitamin B12 levels in patients with oral lichen planus, stomatitis or glossitis.
Folate and vitamin B12 levels in patients with oral lichen planus, stomatitis or glossitis.
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口腔扁平苔藓、口腔炎或舌炎患者的叶酸和维生素 B12 水平。
DOI：
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发表时间：
2001
影响因子：
0.2
通讯作者：
V. Aneksuk
中科院分区：
文献类型：
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作者：
K. Thongprasom;Pornpan Youngnak;V. Aneksuk
41例有口腔病变和症状的患者入组研究。年龄16 ~ 79岁，平均48.5岁。他们被分成两组。Ⅰ组25例口腔扁平苔藓患者，Ⅱ组16例口腔炎或舌炎患者。对他们的全血细胞计数、血红蛋白分型、血清和红细胞叶酸以及血清维生素B12水平进行了研究。结果显示，I组25例患者中有11例（44%）红细胞叶酸水平较低，II组16例患者中有9例（56%）红细胞叶酸水平较低。两组血清维生素B12水平均在正常范围内。他们被定义为叶酸缺乏（n = 10），叶酸缺乏性红细胞生成（n = 3）和叶酸耗竭（n = 7）。所有患者均无贫血和巨红细胞。因此，叶酸水平应调查患者的口腔病变和症状，特别是那些与年龄，营养不良或全身性疾病的危险因素。当怀疑时，应每天补充叶酸。
Forty-one patients with oral lesions and symptoms were enrolled in the study. Their ages ranged from 16 to 79 years with a mean age of 48.5 years. They were divided into two groups. Group I consisted of 25 patients with oral lichen planus and group II consisted of 16 patients with stomatitis or glossitis. Their complete blood counts, hemoglobin typing, serum and red cell folate, and serum vitamin B12 levels were studied. The results revealed low red cell folate levels in 11 out of 25 patients (44%) in group I and 9 out of 16 patients (56%) in group II. The serum vitamin B12 levels were within normal range in both groups. They were defined as having folate deficiency (n = 10), folate deficient erythropoiesis (n = 3) and folate depletion (n = 7). None of them had anemia nor macrocytes. Therefore, folate levels should be investigated in patients with oral lesions and symptoms especially those with risk factors of age, poor nutrition or systemic diseases. When suspected, daily folic acid supplements should be given.
红细胞叶酸水平、口服避孕药的使用和宫颈细胞学异常。
影响因子：
1.8
作者：
Harper,JM;Levine,AJ;Rosenthal,DL;Wiesmeier,E;Hunt,IF;Swendseid,ME;Haile,RW
通讯作者：
Haile,RW