On the origin of event-related potentials indexing covert attentional selection during visual search: timing of selection by macaque frontal eye field and event-related potentials during pop-out search
On the origin of event-related potentials indexing covert attentional selection during visual search: timing of selection by macaque frontal eye field and event-related potentials during pop-out search
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DOI：
10.1152/jn.00549.2012
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发表时间：
2013-01-01
影响因子：
2.5
通讯作者：
Woodman, Geoffrey F.
中科院分区：
文献类型：
--
作者：
Purcell, Braden A.;Schall, Jeffrey D.;Woodman, Geoffrey F.
珀塞尔BA，Schall JD，Woodman GF.视觉搜索过程中内隐注意选择事件相关电位的起源：猕猴额叶眼场和弹出搜索过程中事件相关电位的选择时间。J Neurophysiol 109：557-569，2013.首次发表于2012年10月24日; doi：10.1152/jn.00549.2012.-事件相关电位（ERP）提供了关于心理过程的时间过程的重要数据，但产生ERP成分的神经机制仍然知之甚少。本研究延续了一项研究计划，在该计划中，我们通过同时记录猕猴的颅内和颅外事件相关电位成分的神经基础进行了研究。在这里，我们比较的时间选择的猕猴同源的人类N2 PC组件（m-N2 PC）与选择的时间在额眼场（FEF），一个注意力控制结构被认为会影响后方的视觉领域认为产生的N2 PC。我们记录FEF单单位尖峰和局部场电位（LFPs）的同时与m-N2 pc在猴子执行有效的弹出搜索任务。我们评估了注意力选择的时间如何取决于任务要求，方法是直接与先前在同一只猴子中进行的低效搜索研究进行比较（例如，在Ls中找到T）。通过FEF尖峰、LFP和m-N2 pc的靶选择在高效弹出搜索期间比在低效搜索期间更早。在所有三个信号中选择的时间和幅度在低效但不高效的搜索期间随集合大小而变化。在弹出搜索过程中，注意力选择在m-N2 pc之前的FEF尖峰和LFP中是明显的，遵循在低效搜索过程中观察到的相同序列。这些观察结果是一致的假设，反馈FEF调制神经活动的后部区域，似乎产生的m-N2 PC，即使在视觉场景中的项目之间的注意力竞争是最小的。
Purcell BA, Schall JD, Woodman GF. On the origin of event-related potentials indexing covert attentional selection during visual search: timing of selection by macaque frontal eye field and event-related potentials during pop-out search. J Neurophysiol 109: 557-569, 2013. First published October 24, 2012; doi:10.1152/jn.00549.2012.-Event-related potentials (ERPs) have provided crucial data concerning the time course of psychological processes, but the neural mechanisms producing ERP components remain poorly understood. This study continues a program of research in which we investigated the neural basis of attention-related ERP components by simultaneously recording intracranially and extracranially from macaque monkeys. Here, we compare the timing of attentional selection by the macaque homologue of the human N2pc component (m-N2pc) with the timing of selection in the frontal eye field (FEF), an attentional-control structure believed to influence posterior visual areas thought to generate the N2pc. We recorded FEF single-unit spiking and local field potentials (LFPs) simultaneously with the m-N2pc in monkeys performing an efficient pop-out search task. We assessed how the timing of attentional selection depends on task demands by direct comparison with a previous study of inefficient search in the same monkeys (e.g., finding a T among Ls). Target selection by FEF spikes, LFPs, and the m-N2pc was earlier during efficient pop-out search rather than during inefficient search. The timing and magnitude of selection in all three signals varied with set size during inefficient but not efficient search. During pop-out search, attentional selection was evident in FEF spiking and LFP before the m-N2pc, following the same sequence observed during inefficient search. These observations are consistent with the hypothesis that feedback from FEF modulates neural activity in posterior regions that appear to generate the m-N2pc even when competition for attention among items in a visual scene is minimal.