Sensitivity and specificity of a portable system measuring postural tremor
Sensitivity and specificity of a portable system measuring postural tremor
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DOI：
10.1016/s0892-0362(96)00179-1
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发表时间：
1997-03-01
影响因子：
2.9
通讯作者：
Beuter, A
中科院分区：
文献类型：
--
作者：
Edwards, R;Beuter, A
对一种便携式加速度测量震颤系统进行了评价，即研究了测量的有效性和一致性以及区分病理性和生理性震颤的能力。对照组和帕金森病患者分别使用该便携式系统和一个独立的系统进行测试，该系统使用激光提供精确的位移数据。结果发现，两个系统测量的姿势性震颤幅度存在显著差异，但进一步研究表明，这种差异是由于1）加速度幅度和位移幅度之间的差异，以及2）震颤随测试时间的变化，而不是便携式系统的任何不准确或不可靠性。便携式系统报告的震颤的其他特征在重测实验中也是有效和合理可靠的，除了“谐波指数”，它被证明不太稳定。大多数报告的特征在对照组和帕金森病患者中的分布不同，但当震颤不是很明显时，分布之间的大量重叠将使诊断困难。这些结果表明，直到更好的区分震颤的措施是可用的，震颤测试应重复，并与其他运动功能的测试相结合。(C)1997年爱思唯尔科学公司
A portable, accelerometric system measuring tremor was evaluated, That is, the validity and consistency of measurements as well as its ability to discriminate pathologic from physiological tremor were investigated. Control subjects and patients with Parkinson's disease were tested with this portable system and with an independent system that gave precise displacement data using lasers. It was found that amplitude of postural tremor as measured by the two systems differed significantly, but further investigation revealed that this difference was due 1) to the difference between amplitude of acceleration and amplitude of displacement, and 2) to changes in tremor over the time between tests, rather than to any inaccuracy or unreliability in the portable system. The other characteristics of tremor reported by the portable system were also valid and reasonably reliable in test-retest experiments, with the exception of the ''harmonic index,'' which proved less stable. Most of the reported characteristics were distributed differently for the control group and for the patients with Parkinson's disease, but the large overlaps between distributions would make diagnosis difficult when tremor is not very pronounced. These results suggest that until better discriminating measures of tremor are available, tremor tests should be repeated and combined with other tests of motor function. (C) 1997 Elsevier Science Inc.