Chemically grafted polymeric filters for chemical sensors : Hyperbranched poly(acrylic acid) films incorporating β-cyclodextrin receptors and amine-functionalized filter layers
Chemically grafted polymeric filters for chemical sensors : Hyperbranched poly(acrylic acid) films incorporating β-cyclodextrin receptors and amine-functionalized filter layers
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用于化学传感器的化学接枝聚合物过滤器：结合β-环糊精受体和胺功能化过滤层的超支化聚丙烯酸薄膜
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
R. Crooks
中科院分区：
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作者：
Daniel L. Dermody;R. Peez;D. Bergbreiter;R. Crooks
我们报道了一种新的“分子过滤器”方法来提高化学传感器的选择性。具体来说，我们描述了用金电极包覆β-环糊精功能化、超支化的聚丙烯酸（PAA）薄膜，并在薄膜上覆盖一层化学接枝的超薄多胺层来制备电化学传感器。超支化PAA膜是一种高度功能化的框架，用于共价结合β-环糊精分子受体。接枝的薄多胺层充当ph敏感的“分子过滤器”，选择性地通过适当带电的分析物。聚（胺胺）树状大分子或聚d-赖氨酸用作10 - 15纳米厚的过滤层。结果表明，在低pH下，当多胺被充分质子化时，带正电的氧化还原探针分子，如苯紫素（BV），不会渗透到过滤层中。然而，在高pH下，当过滤层不带电时，BV穿透过滤层并在电极处减少。相反的pH依赖性观察到负…
We report a new “molecular-filter” approach for enhancing the selectivity of chemical sensors. Specifically, we describe electrochemical sensors prepared from Au electrodes coated with β-cyclodextrin-functionalized, hyperbranched poly(acrylic acid) (PAA) films capped with a chemically grafted, ultrathin polyamine layer. The hyperbranched PAA film is a highly functionalized framework for covalently binding the β-cyclodextrin molecular receptors. The thin, grafted polyamine overlayer acts as a pH-sensitive “molecular filter” that selectively passes suitably charged analytes. Poly(amidoamine) dendrimers or poly-d-lysine is used as 10−15-nm-thick filter layers. The results show that at low pH, when the polyamines are fully protonated, positively charged redox probe molecules, such as benzyl viologen (BV), do not permeate the filter layer. However, at high pH, when the filter layer is uncharged, BV penetrates the filter layer and is reduced at the electrode. The opposite pH dependence is observed for negativel...