3D-printing techniques in a medical setting: a systematic literature review.

3D-printing techniques in a medical setting: a systematic literature review.
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DOI:
10.1186/s12938-016-0236-4
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发表时间:
2016-10-21
影响因子:
3.9
通讯作者:
Annemans L
Annemans L
中科院分区:
工程技术3区
文献类型:
--
作者:
Tack P;Victor J;Gemmel P;Annemans L

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三维(3D)打印具有许多应用,并在医学界引起了极大的兴趣。3D打印应用程序质量的不断提高有助于其在患者身上的使用增加。本文总结了关于手术3D打印应用于患者的文献,重点是报告的临床和经济结果。对三个主要的文献数据库进行了病例系列(同一研究中描述的病例超过三个)和3D打印在人类手术中应用的试验的筛选。采用证据表对227篇外科文献进行分析和总结。这些论文描述了3D打印在手术导板、解剖模型和定制植入物中的应用。3D打印用于多个外科领域,例如骨科、颌面外科、颅外科和脊柱外科。一般来说,3D打印部件的优点包括减少手术时间,改善医疗结果和减少辐射暴露。打印和额外扫描的成本通常会增加手术的总成本。3D打印在外科实践和研究中得到了很好的整合。应用范围从主要用于手术计划的解剖模型到手术导向器和植入物。我们的研究表明,3D打印应用有几个优势,但需要进一步研究,以确定增加的干预成本是否可以与这项新技术的可观察优势相平衡。需要进行正式的成本效益分析。本文的在线版本(doi:10.1186/s12938-016-0236-4)包含补充材料,可供授权用户使用。
Three-dimensional (3D) printing has numerous applications and has gained much interest in the medical world. The constantly improving quality of 3D-printing applications has contributed to their increased use on patients. This paper summarizes the literature on surgical 3D-printing applications used on patients, with a focus on reported clinical and economic outcomes. Three major literature databases were screened for case series (more than three cases described in the same study) and trials of surgical applications of 3D printing in humans. 227 surgical papers were analyzed and summarized using an evidence table. The papers described the use of 3D printing for surgical guides, anatomical models, and custom implants. 3D printing is used in multiple surgical domains, such as orthopedics, maxillofacial surgery, cranial surgery, and spinal surgery. In general, the advantages of 3D-printed parts are said to include reduced surgical time, improved medical outcome, and decreased radiation exposure. The costs of printing and additional scans generally increase the overall cost of the procedure. 3D printing is well integrated in surgical practice and research. Applications vary from anatomical models mainly intended for surgical planning to surgical guides and implants. Our research suggests that there are several advantages to 3D-printed applications, but that further research is needed to determine whether the increased intervention costs can be balanced with the observable advantages of this new technology. There is a need for a formal cost–effectiveness analysis. The online version of this article (doi:10.1186/s12938-016-0236-4) contains supplementary material, which is available to authorized users.
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