Intralocular pressure reduction after phacoemulsification with intraocular lens implantation in glaucomatous and nonglaucomatous eyes Evaluation of a causal relationship between the natural lens and open-angle glaucoma
Intralocular pressure reduction after phacoemulsification with intraocular lens implantation in glaucomatous and nonglaucomatous eyes Evaluation of a causal relationship between the natural lens and open-angle glaucoma
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DOI：
10.1016/j.jcrs.2009.05.061
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发表时间：
2009-11-01
影响因子：
2.8
通讯作者：
Schulze, Richard, Jr.
中科院分区：
文献类型：
--
作者：
Poley, Brooks J.;Lindstrom, Richard L.;Schulze, Richard, Jr.
目的：研究超声乳化人工晶状体植入术对非青光眼和青光眼眼的长期影响。地点：明尼苏达州明尼阿波利斯菲利普斯眼科研究所和美国佐治亚州萨凡纳的私人诊所。方法：回顾性评价超声乳化人工晶状体植入术后的眼内压（IOP）。根据术前眼压将眼睛分为5组。记录术前、术后 1 年和最终检查时的数据。分析包括术前 IOP 与 1 年 IOP 和最终 IOP、术后 IOP 升高或降低的眼睛百分比、手术时患者年龄以及术后随访年数。 结果：该研究包括 124 只眼睛。 29至23毫米汞柱组的最终平均眼压降低为8.5毫米汞柱（34%），22至20毫米汞柱组为4.6毫米汞柱（22%），19至18毫米汞柱组为3.4毫米汞柱（18%），17至15毫米汞柱组为1.1毫米汞柱（10%）。在14至5毫米汞柱组中，眼压增加了1.7毫米汞柱（15%）。结论：眼压降低与术前眼压成正比；术前最高眼压下降幅度最大，最低眼压略有上升。一年眼压降低持续了 10 年，并且所有年龄段的患者的情况相似。眼压下降与之前报道的非青光眼眼压下降相似，表明老化的晶状体可能是高眼压和青光眼的主要原因，白内障超声乳化吸出人工晶状体植入术可能有助于预防和治疗成人青光眼。白内障屈光外科杂志，2009； 35:1946-1955 (C) 2009 ASCRS 和 ESCRS
PURPOSE: To study the long-term effects of phacoemulsification with intraocular lens (IOL) implantation in nonglaucomatous and glaucomatous eyes.SETTING: Phillips Eye Institute, Minneapolis, Minnesota, and private practice, Savannah, Georgia, USA.METHODS: Intraocular pressure (IOP) after phacoemulsification with IOL implantation was retrospectively reviewed. Eyes were divided into 5 groups by preoperative IOP. Data were recorded preoperatively, 1 year postoperatively, and at the final check. Analysis included preoperative IOP versus IOP at 1 year and final IOP, percentage of eyes with elevated or reduced IOP postoperatively, patient age at surgery, and years of postoperative follow-up.RESULTS: The study comprised 124 eyes. The final mean IOP reduction was 8.5 mm Hg (34%) in the 29 to 23 mm Hg group, 4.6 mm Hg (22%) in the 22 to 20 mm Hg group, 3.4 mm Hg (18%) in the 19 to 18 mm Hg group, and 1.1 mm Hg (10%) in the 17 to 15 mm Hg group. In the 14 to 5 mm Hg group, IOP increased by 1.7 mm Hg (15%).CONCLUSIONS: Intraocular pressure reduction was proportional to preoperative IOP; the highest preoperative IOPs decreased the most and the lowest increased slightly. One-year IOP reductions were sustained for 10 years and were similar in patients of all ages. The IOP reductions were similar to previously reported reductions in nonglaucomatous eyes, indicating that the aging crystalline lens may be a major cause of ocular hypertension and glaucoma and that phacoemulsification with IOL implantation may help prevent and treat adult glaucoma. J Cataract Refract Surg 2009; 35:1946-1955 (C) 2009 ASCRS and ESCRS