Rat pineal gland suppresses the injection stress-reactive ACTH outflow.
Rat pineal gland suppresses the injection stress-reactive ACTH outflow.
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大鼠松果体抑制注射应激反应性 ACTH 流出。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
M. Demajo
中科院分区：
文献类型：
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作者：
J. Milin;K. Djakovic;M. Demajo
研究了松果体对短期应激诱导的初始 ACTH 反应性流出的调节的参与。应激试验包括在动物后腿皮下注射盐水，引发 ACTH 释放，峰值出现在第 5 分钟，随后在第 15 分钟迅速降至预应激水平。在第 5 分钟监测松果体切除大鼠的较高 ACTH 水平。获得的结果表明松果体在限制初始应激反应 ACTH 流出量方面的作用。
The involvement of the pineal gland in the regulation of the initial ACTH reactive outflow to short-term stress inducement was studied. The stress trial, consisting of the subcutaneous saline injection in the animal hind leg, elicited ACTH release, the peak appearing in the 5th min followed by a rapid downturn to the prestress level in the 15th min. The higher ACTH level in the pinealectomized rats was monitored in the 5th min. The results obtained show the implication of the pineal gland in restricting the magnitude of the initial stress-reactive ACTH outflow.