Chiral Metafilms and Surface Enhanced Raman Scattering for Enantiomeric Discrimination of Helicoid Nanoparticles
Chiral Metafilms and Surface Enhanced Raman Scattering for Enantiomeric Discrimination of Helicoid Nanoparticles
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DOI：
10.1002/adom.202202991
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发表时间：
2022-12
影响因子：
9
通讯作者：
M. Kartau;A. Skvortsova;Victor Tabouillot;Shailendra K. Chaubey;Polina Bainova;Rahul Kumar;V. Burtsev;V. Svorcik;N. Gadegaard;Sang Won Im;M. Urbanova;O. Lyutakov;M. Kadodwala;A. Karimullah
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作者：
M. Kartau;A. Skvortsova;Victor Tabouillot;Shailendra K. Chaubey;Polina Bainova;Rahul Kumar;V. Burtsev;V. Svorcik;N. Gadegaard;Sang Won Im;M. Urbanova;O. Lyutakov;M. Kadodwala;A. Karimullah
手性纳米光子平台提供了一种产生具有增强的不对称性质和强度的近场的方法。它们可以用于光学测量，允许在检测水平上进行对映体辨别，比基于圆偏振光的传统手性灵敏光谱方法所实现的识别能力高6个数量级。表面增强拉曼光谱(SERS)是一种近场环境的局域探测技术。它用于利用非手性分子作为探针来实现对沉积在手性元薄膜的左手和右手对映体上的手性螺旋体纳米粒子的对映体识别。螺旋面和超薄膜的匹配组合(左-左和右-右)会产生“更热”的电磁(EM)热点，而不匹配的组合则会产生明显“冷”的电磁热点。在非手性拉曼报告分子的帮助下，使用SERS可以很容易地检测到这种对热点强度的巨大对映体依赖性。实际上，SERS被用来区分由手性纳米粒子和超薄膜混合产生的等离子体非对映异构体的不同电磁环境。这项工作表明，通过将手性纳米光子平台与已建立的SERS策略相结合，可以在超灵敏手性检测中开辟新的途径。
Chiral nanophotonic platforms provide a means of creating near fields with both enhanced asymmetric properties and intensities. They can be exploited for optical measurements that allow enantiomeric discrimination at detection levels > 6 orders of magnitude than is achieved with conventional chirally sensitive spectroscopic methods based on circularly polarized light. Here it is shown that surface enhanced Raman spectroscopy (SERS) is such a local probe of the near field environment. It is used to achieve enantiomeric discrimination of chiral helicoid nanoparticles deposited on left‐ and right‐handed enantiomorphs of a chiral metafilm using an achiral molecule as a probe. “Hotter” electromagnetic (EM) hotspots are created for matched combinations of helicoid and metafilms (left‐left and right‐right), while mismatched combinations leads to significantly “cooler” electromagnetic hotspots. This large enantiomeric dependency on hotspot intensity is readily detected using SERS with the aid of an achiral Raman reporter molecule. In effect SERS is used to distinguish between the different EM environments of the plasmonic diastereomers produced by mixing chiral nanoparticles and metafilms. The work demonstrates that by combining chiral nanophotonic platforms with established SERS strategies new avenues in ultrasensitive chiral detection can be opened.