Body weight, alcohol consumption and liver enzyme activity - a 4-year follow-up study
Body weight, alcohol consumption and liver enzyme activity - a 4-year follow-up study
复制标题
DOI：
10.1093/ije/30.4.766
复制
发表时间：
2001-08-01
影响因子：
7.7
通讯作者：
Christiani, DC
中科院分区：
文献类型：
--
作者：
Lee, DH;Ha, MH;Christiani, DC
本前瞻性研究旨在调查基线体重指数（BMI）、BMI变化、基线饮酒量、方法对某钢铁公司1994年和1998年进行健康体检的6846名男性工人进行调查。结果天冬氨酸转氨酶（AST）升高的危险性（AST）和丙氨酸氨基转移酶（ALT）值在四年内随基线BMI和BMI变化而增加，但不随饮酒而增加。与受试者BMI相比
Background This prospective study was performed in order to investigate the effect of baseline body mass index (BMI), BMI changes, baseline alcohol consumption, and changes in alcohol consumption on liver enzyme activity.Methods This study population consisted of 6846 male workers in a steel manufacturing company who had undergone health examinations in 1994 and 1998.Results the risk for elevated both aspartate aminotransferase (AST) and alanine aminotransferase (ALT) values over the four years increased with the baseline BMI and BMI changes, but not with alcohol consumption. Compared with the subject BMI